116233-41-1

Upstream product

• 130740-46-4 (5S,6R)-7-Benzyloxy-5-methoxymethoxy-6-methyl-hept-2-yn-4-one 
• 130740-45-3 (2R,3S)-4-Benzyloxy-2-methoxymethoxy-3-methyl-butyraldehyde 
• 95532-13-1 2,2-Dimethyl-propionic acid (2R,3S)-4-benzyloxy-2-hydroxy-3-methyl-butyl ester 
• 59005-41-3 (2R,3S)-4-Benzyloxy-3-methyl-butane-1,2-diol 

Downstream Products

• 116233-37-5 2-[(E)-(S)-1-((1S,2R)-3-Benzyloxy-1-methoxymethoxy-2-methyl-propyl)-1-methyl-but-2-enyloxymethyl]-4,4-dimethyl-4,5-dihydro-oxazole 
• 116233-42-2 (E)-(1R,2S,5S,6R)-7-Benzyloxy-1-(4,4-dimethyl-4,5-dihydro-oxazol-2-yl)-5-methoxymethoxy-2,4,6-trimethyl-hept-3-en-1-ol 
• 116233-42-2 (Z)-(5R,6S)-7-Benzyloxy-1-(4,4-dimethyl-4,5-dihydro-oxazol-2-yl)-5-methoxymethoxy-2,4,6-trimethyl-hept-3-en-1-ol 
• 116233-42-2 (E)-(1R,2S,5R,6S)-7-Benzyloxy-1-(4,4-dimethyl-4,5-dihydro-oxazol-2-yl)-5-methoxymethoxy-2,4,6-trimethyl-hept-3-en-1-ol 
• 116233-37-5 2-[(E)-(S)-1-((1R,2S)-3-Benzyloxy-1-methoxymethoxy-2-methyl-propyl)-1-methyl-but-2-enyloxymethyl]-4,4-dimethyl-4,5-dihydro-oxazole 
• 130740-38-4 (E)-(2S,4S,5R,6S,9R,10S)-11-Benzyloxy-5-methoxy-9-methoxymethoxy-2,6,8,10-tetramethyl-undec-7-ene-1,4-diol 
• 130740-38-4 (E)-(2S,4R,5R,6S,9R,10S)-11-Benzyloxy-5-methoxy-9-methoxymethoxy-2,6,8,10-tetramethyl-undec-7-ene-1,4-diol 
• 130740-50-0 (R)-2-[(2R,3S)-3-((E)-(1R,2S,5R,6S)-7-Benzyloxy-1-methoxy-5-methoxymethoxy-2,4,6-trimethyl-hept-3-enyl)-oxiranyl]-propan-1-ol 
• 130740-50-0 (R)-2-[3-((E)-(1R,2S,5R,6S)-7-Benzyloxy-1-methoxy-5-methoxymethoxy-2,4,6-trimethyl-hept-3-enyl)-oxiranyl]-propan-1-ol 
• 130740-49-7 (3E,7E)-(2S,5S,6S,9R,10S)-11-Benzyloxy-5-methoxy-9-methoxymethoxy-2,6,8,10-tetramethyl-undeca-3,7-dien-1-ol 
• 130766-31-3 (2Z,7E)-(4R,5R,6S,9R,10S)-11-Benzyloxy-5-methoxy-9-methoxymethoxy-6,8,10-trimethyl-undeca-2,7-dien-4-ol 
• 130740-47-5 (E)-(2R,3S,6R,7S)-8-Benzyloxy-2-methoxy-6-methoxymethoxy-3,5,7-trimethyl-oct-4-en-1-ol 
• 116233-37-5 2-[(E)-1-((1R,2S)-3-Benzyloxy-1-methoxymethoxy-2-methyl-propyl)-1-methyl-but-2-enyloxymethyl]-4,4-dimethyl-4,5-dihydro-oxazole 

Relevant academic research and scientific papers

SYNTHESIS OF ANTITUMOR ANSAMYCINS. 1. SERIAL SIGMATROPIC CONSTRUCTION OF THE C11-C21 ANSA SUBUNIT OF MACBECIN I

Diol 4, comprising the C11-C21 ansa subunit of the antitumor antibiotic macbecin I, has been prepared by a sequence incorporating sequential Wittig rearrangements to establish the carbon skeleton and remote functionality of the macbecin ansa system.