116233-42-2

Upstream product

• 116233-37-5 2-[(E)-1-((1R,2S)-3-Benzyloxy-1-methoxymethoxy-2-methyl-propyl)-1-methyl-but-2-enyloxymethyl]-4,4-dimethyl-4,5-dihydro-oxazole 
• 116233-37-5 2-[(E)-(S)-1-((1R,2S)-3-Benzyloxy-1-methoxymethoxy-2-methyl-propyl)-1-methyl-but-2-enyloxymethyl]-4,4-dimethyl-4,5-dihydro-oxazole 
• 74307-97-4 2-chloromethyl-4,4-dimethyl-4,5-dihydro-1,3-oxazole 
• 116233-41-1 (E)-(4S,5R,6S)-7-Benzyloxy-5-methoxymethoxy-4,6-dimethyl-hept-2-en-4-ol 
• 59005-41-3 (2R,3S)-4-Benzyloxy-3-methyl-butane-1,2-diol 
• 95532-13-1 2,2-Dimethyl-propionic acid (2R,3S)-4-benzyloxy-2-hydroxy-3-methyl-butyl ester 
• 130740-45-3 (2R,3S)-4-Benzyloxy-2-methoxymethoxy-3-methyl-butyraldehyde 
• 116233-41-1 (E)-(5R,6S)-7-Benzyloxy-5-methoxymethoxy-4,6-dimethyl-hept-2-en-4-ol 
• 130740-46-4 (5S,6R)-7-Benzyloxy-5-methoxymethoxy-6-methyl-hept-2-yn-4-one 

Downstream Products

• 130740-47-5 (E)-(2R,3S,6R,7S)-8-Benzyloxy-2-methoxy-6-methoxymethoxy-3,5,7-trimethyl-oct-4-en-1-ol 
• 130766-31-3 (2Z,7E)-(4R,5R,6S,9R,10S)-11-Benzyloxy-5-methoxy-9-methoxymethoxy-6,8,10-trimethyl-undeca-2,7-dien-4-ol 
• 130740-49-7 (3E,7E)-(2S,5S,6S,9R,10S)-11-Benzyloxy-5-methoxy-9-methoxymethoxy-2,6,8,10-tetramethyl-undeca-3,7-dien-1-ol 
• 130740-50-0 (R)-2-[3-((E)-(1R,2S,5R,6S)-7-Benzyloxy-1-methoxy-5-methoxymethoxy-2,4,6-trimethyl-hept-3-enyl)-oxiranyl]-propan-1-ol 
• 130740-50-0 (R)-2-[(2R,3S)-3-((E)-(1R,2S,5R,6S)-7-Benzyloxy-1-methoxy-5-methoxymethoxy-2,4,6-trimethyl-hept-3-enyl)-oxiranyl]-propan-1-ol 
• 130740-38-4 (E)-(2S,4R,5R,6S,9R,10S)-11-Benzyloxy-5-methoxy-9-methoxymethoxy-2,6,8,10-tetramethyl-undec-7-ene-1,4-diol 

Relevant academic research and scientific papers

SYNTHESIS OF ANTITUMOR ANSAMYCINS. 1. SERIAL SIGMATROPIC CONSTRUCTION OF THE C11-C21 ANSA SUBUNIT OF MACBECIN I

Diol 4, comprising the C11-C21 ansa subunit of the antitumor antibiotic macbecin I, has been prepared by a sequence incorporating sequential Wittig rearrangements to establish the carbon skeleton and remote functionality of the macbecin ansa system.

Diastereoselective Wittig Rearrangement of Tertiary Allylic Ethers

The Wittig rearrangement of oxazoline ethers of α-alkoxy, tertiary allylic alcohols affords a diastereoselective entry to remotely fuctionalized trisubstituted olefins; the stereochemistry of the rearrangement is directed by a stereogenic center ext