116386-53-9

Basic information

• Product Name: Benzene, 1-[(R)-[(1R)-1-chloro-2-phenylethyl]sulfinyl]-4-methyl-
• CAS NO: 116386-53-9
• Molecular Formula: C15H15ClOS
• Molecular Weight: 278.803
• Mol File: 116386-53-9.mol
• Article Data: 5

Chemical Properties

• CAS DataBase Reference: Benzene, 1-[(R)-[(1R)-1-chloro-2-phenylethyl]sulfinyl]-4-methyl-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzene, 1-[(R)-[(1R)-1-chloro-2-phenylethyl]sulfinyl]-4-methyl-(116386-53-9)
• EPA Substance Registry System: Benzene, 1-[(R)-[(1R)-1-chloro-2-phenylethyl]sulfinyl]-4-methyl-(116386-53-9)

Safety Data

• Hazardous Substances Data: 116386-53-9(Hazardous Substances Data)

Upstream product

• 31350-92-2 (+)-(S_S)-chloromethyl (4-methylphenyl) sulfoxide 
• 118271-35-5 (R_S)-2-phenylethyl p-tolyl sulfoxide 
• 824-79-3 sodium 4-methylbenzenesulfinate 
• 1517-82-4 (1R,2S,5R,SS)-(-)-menthyl p-toluenesulfinate 
• 10439-23-3 4-methylbenzenesulfinyl chloride 
• 31350-91-1 (R)-chloromethyl p-tolyl sulfoxide 
• 100-39-0 benzyl bromide 
• 1517-82-4 (-)-menthyl p-toluenesulfinate 
• 1519-39-7 (R)-methyl p-tolyl sulfoxide 
• 3277-89-2 phenethylmagnesium bromide 

Downstream Products

• 121174-11-6 (R)-3-Chloro-2-methyl-4-phenyl-3-((R)-toluene-4-sulfinyl)-butan-2-ol 
• 1519-40-0 (+)-(R)-ethyl p-tolyl sulfoxide 
• 30506-35-5 butyl(p-tolyl)sulfoxide 
• 622-24-2 2-phenylethyl chloride 
• 117326-73-5 (-)-(2R,3R)-2,3-epoxy-1-(tert-butyldimethylsiloxy)-2-methyl-4-phenyl-3-(p-tolylsulfinyl)butane 
• 117406-97-0 (-)-(2S,3R)-2,3-epoxy-1-(tert-butyldimethylsiloxy)-2-methyl-4-phenyl-3-(p-tolylsulfinyl)butane 
• 117326-75-7 (E)-(S)-1-(tert-Butyl-dimethyl-silanyloxy)-2-methyl-4-phenyl-but-3-en-2-ol 
• 117326-74-6 (-)-(2R,3S)-2,3-epoxy-2-methyl-4-phenylbutan-1-ol 
• 121174-16-1 (2R,3R)-2-Benzyl-3-methyl-2-((R)-toluene-4-sulfinyl)-oxirane 
• 121249-32-9 (2R,3S)-2-Benzyl-3-methyl-2-((R)-toluene-4-sulfinyl)-oxirane 
• 121174-18-3 (S)-4-Hydroxy-3-methyl-1-phenyl-3-piperidin-1-yl-butan-2-one 
• 121174-17-2 (R)-4-Hydroxy-3-methyl-1-phenyl-3-piperidin-1-yl-butan-2-one 
• 117326-77-9 [(2S,3R)-3-Benzyl-3-(tert-butyl-dimethyl-silanyl)-2-methyl-oxiranyl]-methanol 

Relevant articles and documents

A NOVEL APPROACH TO THE SYNTHESIS OF CHIRAL EPOXIDES AND ALLYLIC ALCOHOLS BY THE USE OF OPTICALLY ACTIVE p-TOLYL SULFINYL GROUP AS A CHIRAL AUXILILIARY

A Novel synthesis of chiral epoxides and allylic alcohols was realized from (-)-chloromethyl p-tolyl sulfoxide and carbonyl compounds through the α,β-epoxy sulfoxides.The procedure and a stereochemistry of the asymmetric induction of the reaction are repo

Highly enantiomerically enriched α-haloalkyl grignard reagents

α-Chloro- and α-bromoalkyl Grignard reagents 11 and 30 with > 97% ee (enantiomeric excess) were generated by a sulfoxide/magnesium exchange reaction from the enantiomerically and diastereomerically pure sulfoxides 25 and 27. The resulting α-haloalkyl Grig

THE PRACTICAL PROCEDURE FOR A PREPARATION OF 1-CHLOROALKYL p-TOLYL SULFOXIDES IN HIGH OPTICALLY ACTIVE FORM: A VERY SHORT SYNTHESIS OF OPTICALLY ACTIVE DISPARLURE

A chlorination of optically active alkyl p-tolyl sulfoxides with N-chlorosuccinimide in dichloromethane in the presence of potassium carbonate afforded optically active 1-chloroalkyl p-tolyl sulfoxides in 87-94percent ee (88-94percent chemical yields).The optically active chloroalkyl sulfoxide was applied to a synthesis of optically active (+)-disparlure.