116436-10-3 Usage
Uses
Used in Organic Synthesis:
N-(5-BROMO-2-METHYLPHENYL)ACETAMIDE is utilized as a key intermediate in organic synthesis for the preparation of various chemical compounds. Its unique structure allows for the formation of new bonds and the synthesis of complex molecules, making it an essential component in the creation of a wide range of chemical products.
Used in Pharmaceutical Research:
In the pharmaceutical industry, N-(5-BROMO-2-METHYLPHENYL)ACETAMIDE is employed as a building block for the development of new drugs and biologically active molecules. Its structural features and reactivity make it a versatile component in the design and synthesis of potential therapeutic agents, contributing to the advancement of medicinal chemistry.
Used in Drug Development:
N-(5-BROMO-2-METHYLPHENYL)ACETAMIDE plays a significant role in drug development, where it is used to create new pharmaceutical agents with improved efficacy and selectivity. Its unique properties enable the design of molecules that can target specific biological pathways, potentially leading to the discovery of more effective treatments for various diseases and conditions.
Used in Medicinal Chemistry Research:
In the field of medicinal chemistry, N-(5-BROMO-2-METHYLPHENYL)ACETAMIDE is an important research tool for studying the structure-activity relationships of drug candidates. Its incorporation into various molecular frameworks allows researchers to explore the impact of specific structural modifications on the biological activity and pharmacokinetic properties of drug molecules, ultimately contributing to the optimization of drug candidates for clinical use.
Check Digit Verification of cas no
The CAS Registry Mumber 116436-10-3 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,1,6,4,3 and 6 respectively; the second part has 2 digits, 1 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 116436-10:
(8*1)+(7*1)+(6*6)+(5*4)+(4*3)+(3*6)+(2*1)+(1*0)=103
103 % 10 = 3
So 116436-10-3 is a valid CAS Registry Number.
116436-10-3Relevant academic research and scientific papers
Direct para-Selective C-H Amination of Iodobenzenes: Highly Efficient Approach for the Synthesis of Diarylamines
Chen, Yujie,Huang, Zhibin,Jiang, Yaqiqi,Shu, Sai,Yang, Shan,Shi, Da-Qing,Zhao, Yingsheng
, p. 8226 - 8235 (2021/06/28)
Iodine(III)-mediated synthesis of 4-iodo-N-phenylaniline from iodobenzene has been achieved, and the reaction can proceed under mild conditions. A variety of functional groups were well tolerated, providing the corresponding products in moderate to good yields. The remaining iodine group provides an effective platform for converting the products into several valuable asymmetric diphenylamines. Most importantly, this reaction can be easily scaled up to the ten-gram scale, highlighting its synthetic utility. The mechanistic study revealed that the in situ generated aryl hypervalent iodine intermediate is the key factor to realize this para-selective C-H amination reaction.
Sulfonium Salts as Alkylating Agents for Palladium-Catalyzed Direct Ortho Alkylation of Anilides and Aromatic Ureas
Simkó, Dániel Cs.,Elekes, Péter,Pázmándi, Vivien,Novák, Zoltán
, p. 676 - 679 (2018/02/09)
A novel method for the ortho alkylation of acetanilide and aromatic urea derivatives via C-H activation was developed. Alkyl dibenzothiophenium salts are considered to be new reagents for the palladium-catalyzed C-H activation reaction, which enables the transfer of methyl and other alkyl groups from the sulfonium salt to the aniline derivatives under mild catalytic conditions.
SUBSTITUTED QUINOXALINE DERIVATIVES
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Page/Page column 312, (2016/12/01)
The present invention relates to substituted quinoxaline derivatives. These compounds are useful for the prevention and/or treatment of several medical conditions including hyperproliferative disorders and diseases.
