116436-10-3

Basic information

• Product Name: N-(5-BROMO-2-METHYLPHENYL)ACETAMIDE
• Synonyms: N-(5-BROMO-2-METHYLPHENYL)ACETAMIDE;2-Acetamido-4-bromotoluene;N-Acetyl 5-bromo-2-methylaniline;AcetaMide, N-(5-broMo-2-Methylphenyl)-;2-ACETYLAMINO-4-BROMOTOLUENE
• CAS NO: 116436-10-3
• Molecular Formula: C₉H₁₀BrNO
• Molecular Weight: 228.09
• Mol File: 116436-10-3.mol
• Article Data: 4

Chemical Properties

• Appearance: /
• Storage Temp.: Sealed in dry,Room Temperature
• CAS DataBase Reference: N-(5-BROMO-2-METHYLPHENYL)ACETAMIDE(CAS DataBase Reference)
• NIST Chemistry Reference: N-(5-BROMO-2-METHYLPHENYL)ACETAMIDE(116436-10-3)
• EPA Substance Registry System: N-(5-BROMO-2-METHYLPHENYL)ACETAMIDE(116436-10-3)

Safety Data

• Hazardous Substances Data: 116436-10-3(Hazardous Substances Data)

Usage

General Description

N-(5-Bromo-2-methylphenyl)acetamide is a chemical compound with the molecular formula C9H10BrNO. It is an acetamide derivative with a substituent of bromine and methyl on its phenyl ring. N-(5-BROMO-2-METHYLPHENYL)ACETAMIDE is commonly used in organic synthesis and pharmaceutical research as a building block for creating new drugs and biologically active molecules. Its properties and structure make it a promising candidate for drug development and medicinal chemistry research. Furthermore, it is important to handle this chemical with care and adhere to safety protocols due to its potential hazards and risks associated with its handling and storage.

Upstream product

• 6358-77-6 5-bromo-2-methoxyaniline 
• 75-36-5 acetyl chloride 
• 621-38-5 3-bromoacetanilide 
• 112359-25-8 5-(trifluoromethyl)dibenzothiophenium trifluoromethanesulfonate 
• 591-19-5 m-Bromoaniline 
• 39478-78-9 5-bromo-2-methylaniline 
• 60956-26-5 4-bromo-2-nitrotoluene 
• 7664-93-9 sulfuric acid 
• 108-24-7 acetic anhydride 

Downstream Products

• 1157928-89-6 5-bromo-N-ethyl-2-methylaniline 
• 244256-21-1 4-bromo-2-[(N-carboxymethyl)amino]benzoic acid 
• 114306-17-1 3-acetoxy-6-bromoindole 
• 859184-22-8 2-amino-4-bromo-benzoic acid-(2-chloro-ethyl ester) 
• 20776-50-5 2-amino-4-bromobenzoic acid 
• 286461-70-9 4-Acetylamino-2-bromo-5-methyl-benzenesulfonyl chloride 
• 101861-53-4 2-(methylcarbonylamino)-4-bromobenzoic acid 

Relevant articles and documents

Direct para-Selective C-H Amination of Iodobenzenes: Highly Efficient Approach for the Synthesis of Diarylamines

Iodine(III)-mediated synthesis of 4-iodo-N-phenylaniline from iodobenzene has been achieved, and the reaction can proceed under mild conditions. A variety of functional groups were well tolerated, providing the corresponding products in moderate to good yields. The remaining iodine group provides an effective platform for converting the products into several valuable asymmetric diphenylamines. Most importantly, this reaction can be easily scaled up to the ten-gram scale, highlighting its synthetic utility. The mechanistic study revealed that the in situ generated aryl hypervalent iodine intermediate is the key factor to realize this para-selective C-H amination reaction.

SUBSTITUTED QUINOXALINE DERIVATIVES

The present invention relates to substituted quinoxaline derivatives. These compounds are useful for the prevention and/or treatment of several medical conditions including hyperproliferative disorders and diseases.