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3-(4-METHOXYPHENYL)CYCLOPENTANONE is a chemical with a specific purpose. Lookchem provides you with multiple data and supplier information of this chemical.

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  • 116526-34-2 Structure
  • Basic information

    1. Product Name: 3-(4-METHOXYPHENYL)CYCLOPENTANONE
    2. Synonyms: 3-(4-METHOXYPHENYL)CYCLOPENTANONE
    3. CAS NO:116526-34-2
    4. Molecular Formula: C12H14O2
    5. Molecular Weight: 190.24
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 116526-34-2.mol
  • Chemical Properties

    1. Melting Point: 47-49 °C
    2. Boiling Point: 319.3±42.0 °C(Predicted)
    3. Flash Point: N/A
    4. Appearance: /
    5. Density: 1.097±0.06 g/cm3(Predicted)
    6. Refractive Index: N/A
    7. Storage Temp.: N/A
    8. Solubility: N/A
    9. CAS DataBase Reference: 3-(4-METHOXYPHENYL)CYCLOPENTANONE(CAS DataBase Reference)
    10. NIST Chemistry Reference: 3-(4-METHOXYPHENYL)CYCLOPENTANONE(116526-34-2)
    11. EPA Substance Registry System: 3-(4-METHOXYPHENYL)CYCLOPENTANONE(116526-34-2)
  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 116526-34-2(Hazardous Substances Data)

116526-34-2 Usage

Synthesis Reference(s)

Tetrahedron Letters, 29, p. 2111, 1988 DOI: 10.1016/S0040-4039(00)87848-X

Check Digit Verification of cas no

The CAS Registry Mumber 116526-34-2 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,1,6,5,2 and 6 respectively; the second part has 2 digits, 3 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 116526-34:
(8*1)+(7*1)+(6*6)+(5*5)+(4*2)+(3*6)+(2*3)+(1*4)=112
112 % 10 = 2
So 116526-34-2 is a valid CAS Registry Number.

116526-34-2SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 13, 2017

Revision Date: Aug 13, 2017

1.Identification

1.1 GHS Product identifier

Product name 3-(4-methoxyphenyl)cyclopentan-1-one

1.2 Other means of identification

Product number -
Other names -

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:116526-34-2 SDS

116526-34-2Relevant articles and documents

BCL-2 INHIBITOR

-

Paragraph 0730-0732, (2021/10/22)

Disclosed herein is a compound of Formula (I) for inhibiting both Bcl-2 wild type and mutated Bcl-2, in particular, Bcl-2 G101V and D103Y, and a method of using the compound disclosed herein for treating dysregulated apoptotic diseases.

2-allyl-1-oxo-2, 3-dihydro-1, 2-benzisothiazole

-

Paragraph 0033; 0048, (2017/02/02)

The invention discloses chiral 2-allyl-1-oxo-2, 3-dihydro-1, 2-benzisothiazole and its preparation method and use. The chiral 2-allyl-1-oxo-2, 3-dihydro-1, 2-benzisothiazole is a racemate or an optical isomer shown in the formula I and is characterized in

4,8-disubstituted bicyclo[3.3.1]nona-2,6-dienes as chiral ligands for rh-catalyzed asymmetric 1,4-addition reactions

Rimkus, Renaldas,Jurgelenas, Marius,Ston?ius, Sigitas

supporting information, p. 3017 - 3021 (2015/05/13)

C2-symmetric chiral diene ligands based on 4,8-endo,endo-disubstituted bicyclo[3.3.1]nona-2,6-diene framework have been designed and synthesized. The rhodium complexes of the dienes, which were obtained in a few straightforward steps from enantiomerically pure bicyclo[3.3.1]nonane-2,6-dione, exhibited excellent catalytic activity and high enantioselectivity (up to 96% ee) in the conjugate addition reaction of arylboronic acids to cyclic enones under mild reaction conditions with high atom efficiency. Chiral C2-symmetric 4,8-endo,endo-disubstituted bicyclo[3.3.1]nona-2,6-diene ligands were synthesized from easily available bicyclo[3.3.1]nonane-2,6-dione and utilized in the asymmetric 1,4-addition reaction of arylboronic acids to cyclic enones. The catalyst prepared in situ from ligand 4b and [RhCl(C2H4)2]2 exhibited excellent catalytic activity and high enantioselectivity (up to 96% ee) under mild reaction conditions with high atom efficiency.

Triazolium salts as appropriate catalytic scaffolds for 1,4-additions to α,β-unsaturated carbonyls

Bratko, Ielyzaveta,Guisado-Barrios, Gregorio,Favier, Isabelle,Mallet-Ladeira, Sonia,Teuma, Emmanuelle,Peris, Eduardo,Gomez, Montserrat

, p. 2160 - 2167 (2014/04/17)

1,2,3-Triazole derivatives containing a rigid dihydroanthracenyl skeleton are suitable precursors for both organometallic and organo-based catalysts. A Rh-carbene complex and the triazolium salt efficiently catalyzed the 1,4-additions of C- and heterodonor reagents to α,β-unsaturated carbonyl substrates, respectively. Copyright

Ligand- and base-free Pd(II)-catalyzed controlled switching between oxidative heck and conjugate addition reactions

Walker, Sarah E.,Boehnke, Julian,Glen, Pauline E.,Levey, Steven,Patrick, Lisa,Jordan-Hore, James A.,Lee, Ai-Lan

supporting information, p. 1886 - 1889 (2013/06/04)

A simple change of solvent allows controlled and efficient switching between oxidative Heck and conjugate addition reactions on cyclic Michael acceptor substrates, catalyzed by a cationic Pd(II) catalyst system. Both reactions are ligand- and base-free and tolerant of air and moisture, and the controlled switching sheds light on some of the factors which favor one reaction over the other.

CYCLIC AMINE SUBSTITUTED OXAZOLIDINONE CETP INHIBITOR

-

Page/Page column 101; 102, (2012/05/19)

CCompounds having the structure of Formula I, including pharmaceutically acceptable salts of the compounds, are CETP inhibitors and are useful for raising HDL-cholesterol, reducing LDL-cholesterol, and for treating or preventing atherosclerosis. In the compound of Formula I, A3 is a substitiuted phenyl group or indanyl group.Formula (I)

N-heterocyclic carbene-rhodium(I) complexes derived from proline for the 1,4-conjugate addition of arylboronic acids to enones in neat water

Tang, Yi-Qiang,Lv, Huan,He, Xiao-Na,Lu, Jian-Mei,Shao, Li-Xiong

experimental part, p. 705 - 708 (2012/01/07)

N-Heterocyclic carbene-rhodium(I) complexes derived from N-benzyl substituted proline have been successfully synthesized and were found to be efficient catalysts for the 1,4-conjugate addition of arylboronic acids to enones in neat water at 40 °C. Under the optimal reaction conditions, all reactions gave the addition products in good to high yields.

Catalytic and regioselective ring expansion of arylcyclobutanones with trimethylsilyldiazomethane. Ligand-dependent entry to β-ketosilane or enolsilane adducts

Dabrowski, Jennifer A.,Moebius, David C.,Wommack, Andrew J.,Kornahrens, Anne F.,Kingsbury, Jason S.

supporting information; experimental part, p. 3598 - 3601 (2010/11/04)

Divergent reactivity is uncovered in the homologation of arylcyclobutanones with trimethylsilyldiazomethane. With Sc(OTf)3 as catalyst, enolsilanes are obtained with a high preference for methylene migration. By contrast, Sc(hfac)3 g

PH-Dependent conjugate addition of arylboronic acids to α,β-unsaturated enones catalyzed by a reusable palladium(II)/cationic 2,2'-bipyridyl system in water under air

Huang, Shao-Hsien,Wu, Tzu-Min,Tsai, Fu-Yu

experimental part, p. 619 - 624 (2010/11/04)

A reusable Pd(NH3)2Cl2/cationic 2,2'-bipyridyl system for the catalysis of the conjugate addition of arylboronic acids to α,β-unsaturated enones in water under air was developed. Addition of arylboronic acids to both cyclic and acyclic enones progressed smoothly, providing the products in good to high yields, the best result being obtained when HBF4 was used to adjust the pH value to 1.0. After the reaction, the residual aqueous solution could be reused several times,making the reaction greener and reducing wastage of precious metals. Copyright

Michael addition reactions with η2-coordinaied anisoles: Controlling the stereochemistry of the para and benzylic carbons

Smith, Philip L.,Keane, Joseph M.,Shankman, Sarah E.,Chordia, Mahendra D.,Harman, W. Dean

, p. 15543 - 15551 (2007/10/03)

Several η2-coordinated anisole complexes were treated with various Michael acceptors in the presence of a Lewis or Br?nsted acid to generate stable 4H-anisolium complexes. These reactions were found to proceed with high stereochemical control with predictable outcomes, provided that the moderate acid (NH2Ph2)OTf was used and the complex was dissolved in an acidic solution. The stereochemistry is shown to originate from an unexpectedly high preference for one coordination diastereomer of the anisole complex in the solid state and a Diels-Alder like transition state for the Michael reaction.

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