116597-14-9Relevant academic research and scientific papers
Study on disulfur-backboned nucleic acid: Part 1, efficient synthesis of 3′,5′-dithio-2′-deoxyadenosine
Zheng, Hongchao,Cheng, Changmei,Wang, Hua,Xu, Shanshan,Zhao, Yufen
, p. 2585 - 2587 (2004)
An efficient procedure is established to synthesize 3′,5′- dithio-2′-deoxyadenosine starting from 2′-deoxyadenosine in five steps in 33% overall yield. In this procedure, the key intermediate 9 was synthesized by twice SN2 reactions with twice
Deoxynucleic guanidine: Synthesis and incorporation of purine nucleosides into positively charged DNG oligonucleotides
Challa, Hemavathi,Bruice, Thomas C.
, p. 1475 - 1481 (2007/10/03)
The synthesis of purine nucleosides capable of making the guanidinium linkage is described for the first time starting from the corresponding 2′-deoxynucleosides. The positively charged mixed base DNG oligomer containing guanine was synthesized on solid-p
Synthesis and application of 3′-amino-dye-terminators for dna sequencing
Wojczcwski,Faulstich,Engels
, p. 751 - 754 (2007/10/03)
The synthesis of 3′-aminomodified nucleoside 5′-triphosphates and their coupling with oligoaminoacid-linked dyes is described. Application for DNA dye-terminator sequencing was investigated. Copyright 1997 by Marcel Dekker, Inc.
Anchimeric Assistance of a 5'-O-Carbonyl Function for Inversion of Configuration at the 3'-Carbon Atom of 2'-Deoxyadenosine. Synthesis of 3'-Azido-2',3'-dideoxyadenosine and 3'-Azido-2',3'-dideoxyinosine
Herdewijn, Piet A. M.
, p. 5050 - 5053 (2007/10/02)
3'-Azido-2',3'-dideoxyadenosine was synthesized in two steps from N6,5'-O-dibenzoyl-2'-deoxyadenosine in 65percent yield.The configuration at the 3' position was inverted by reaction of N6,5'-O-dibenzoyl-2'-deoxyadenosine with trifli
