116831-08-4Relevant articles and documents
Catalytic asymmetric Michael reaction promoted by the La-Na-BINOL complex (LSB). Enantioface selection on Michael donors
Sasai, Hiroaki,Emori, Eita,Arai, Takayoshi,Shibasaki, Masakatsu
, p. 5561 - 5564 (1996)
LSB can efficiently promote catalytic asymmetric Michael reactions in CH2Cl2, inducing high enantiomeric excesses on the Michael donor side. The multifunctional character of LSB appears to give rise to high stereoselectivity, offerin
Synthesis of optically active α,α-distubstituted β-keto esters via chiral β-enamino esters
Guingant,Hammami
, p. 411 - 414 (2007/10/02)
Michael addition of chiral β-enamino esters to MVK and acrylates promoted by Lewis acids (ZnCl2, MgBr2) or high pressure (11-14 Kbar) afforded, after hydrolytic work-up, α,α-disubstituted β-keto esters in good enantiomeric carbon exc
CHLOROTRIMETHYLSILANE PROMOTED ASYMMETRIC MICHAEL REACTION OF CHIRAL ENAMINES OF α-ALKYL β-KETO ESTERS
Tomioka, Kiyoshi,Seo, Wonjun,Ando, Kaori,Koga, Kenji
, p. 6637 - 6640 (2007/10/02)
By the promotion of chlorotrimethylsilane, asymmetric Michael reaction of the chiral enamines (2) of α-alkyl β-keto esters (1) with methyl vinyl ketone and ethyl acrylate proceeded to afford, after hydrolysis, either enantiomer of the corresponding adduct
