117-21-5

Basic information

• Product Name: 3-CHLOROPHTHALIC ANHYDRIDE
• Synonyms: 4-chloro-1,3-dihydro-2-benzofuran-1,3-dione;4-Chloro-2-benzofuran-1,3-dione, 4-Chloroisobenzofuran-1,3-dione;1,3-Isobenzofurandione, 4-chloro-;Ktoyupd;3-CHLOROPHTHALIC ACID ANHYDRIDE;3-CHLOROPHTHALIC ANHYDRIDE;4-Chloro-isobenzofuran-1,3-dione;3-CHLOROPHTHALIC ANHYDRIDE 98%
• CAS NO: 117-21-5
• Molecular Formula: C₈H₃ClO₃
• Molecular Weight: 182.56
• EINECS: 204-179-8
• Product Categories: Anhydride;API Intermediate;Acids and Derivatives;Phthalic Acids, Esters and Derivatives;API intermediates
• Mol File: 117-21-5.mol
• Article Data: 7

Chemical Properties

• Melting Point: 123-126 °C
• Boiling Point: 170°C(lit.)
• Flash Point: 152.2 °C
• Appearance: White or pale yellow/Crystalline Powder and Chunks
• Density: 1.594 g/cm³
• Vapor Pressure: 0.000392mmHg at 25°C
• Refractive Index: 1.626
• Storage Temp.: Inert atmosphere,Room Temperature
• CAS DataBase Reference: 3-CHLOROPHTHALIC ANHYDRIDE(CAS DataBase Reference)
• NIST Chemistry Reference: 3-CHLOROPHTHALIC ANHYDRIDE(117-21-5)
• EPA Substance Registry System: 3-CHLOROPHTHALIC ANHYDRIDE(117-21-5)

Safety Data

• Hazard Codes: Xi
• Statements: 36/37/38
• Safety Statements: 37/39-26
• Hazardous Substances Data: 117-21-5(Hazardous Substances Data)

Usage

Chemical Properties

White or pale yellow crystalline powder and chunks

Uses

3-chlorophthalic anhydride is mainly used for the synthesis of polyimide engineering plastic properties. Also be used as drug or pesticide intermediates.

InChI:InChI=1/C8H3ClO3/c9-5-3-1-2-4-6(5)8(11)12-7(4)10/h1-3H

Upstream product

• 85-44-9 phthalic anhydride 
• 56-23-5 tetrachloromethane 
• 641-70-3 3-nitrophthalic acid anhydride 
• 1825-30-5 1,5-dichloronaphthalene 
• 824-72-6 P,P-dichlorophenylphosphine oxide 
• 89-20-3 4-chlorophthalic acid 
• 27563-65-1 3-chlorobenzene-1,2-dicarboxylic acid 
• 88-99-3 benzene-1,2-dicarboxylic acid 
• 603-11-2 3-nitrophthalic acid 
• 86-57-7 1-Nitronaphthalene 
• 7499-08-3 3-chloro-2-methylbenzoic acid 
• 81697-42-9 1,10-Dichloro-5H-dibenzo[b,e]azepine-6,11-dione 
• 608-23-1 3-chloro-o-xylene 
• 90-13-1 1-Chloronaphthalene 

Downstream Products

• 101272-88-2 3-chloro-2-(2,4-dimethyl-benzoyl)-benzoic acid 
• 582303-34-2 4,4'-bis(3-chlorophthalimido)-3,3'-dimethyldiphenylmethane 
• 95834-45-0 2,2'-bis<4-chloro-2-(4''-dimethylaminophenyl)indan-1,3-dione> 
• 52256-80-1 2,2-bis[4-(2,3-dicarboxyphenoxy)phenyl]propane dianhydride 
• 113770-84-6 3-chloro-phthaloyl dichloride 
• 1417785-08-0 3-chloro-N-(3-cyano-1-(2,6-dichloro-4-(trifluoromethyl)phenyl)-1H-pyrazol-5-yl)-N-isopropylphthalamide 
• 645386-66-9 3-chloro-2-(isopropylcarbamoyl)benzoic acid 
• 1623101-11-0 3-chloro-N-[3-chloro-4-(4-chloro-1,3-dihydro-1,3-dioxo-2H-isoindol-2-yl)phenyl]-2-pyridinecarboxamide 
• 1202803-96-0 4-((7-chloro-1-(4-chlorophenyl)-1-((1-(hydroxymethyl)cyclopropyl)methoxy)-3-oxoisoindolin-2-yl)methyl)benzonitrile 
• 1202803-93-7 4-((7-chloro-1-(4-chlorophenyl)-1-hydroxy-3-oxoisoindolin-2-yl)methyl)benzonitrile 
• 1202803-97-1 2-(4-bromobenzyl)-4-chloro-3-(4-chlorophenyl)-3-((1-(hydroxymethyl)cyclopropyl)methoxy)isoindolin-1-one 
• 1202803-95-9 2-(4-bromobenzyl)-4-chloro-3-(4-chlorophenyl)-3-hydroxyisoindolin-1-one 

Related news

Thermodynamic properties of 3-CHLOROPHTHALIC ANHYDRIDE (cas 117-21-5) and 4-chlorophthalic anhydride and their application for purification method development08/25/2019

Development and design of crystallization process strongly depend on accurate solid-liquid equilibrium data. In this paper, the solubility of 3-chlorophthalic anhydride and 4-chlorophthalic anhydride in methyl acetate + cyclohexane binary solvent mixtures was determined from T = (283.15 to 328.1...detailed

Relevant articles and documents

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Processes using a phosphorus complex

A process for chlorinating compounds containing a carbon atom bonded to a hetero-atom selected from the group consisting of oxygen, nitrogen and sulfur; said process comprises contacting the carbon hetero-atom containing compound with a chloro phosphorus complex of the formula wherein R is selected from the group consisting of aryl, substituted aryl, alkyl and substituted alkyl, so that the hetero-atom is replaced by at least one chlorine atom; compounds capable of being chlorinated can include, for example, carboxylic acids, acid chlorides, ketones, aldehydes, alcohols, epoxides, esters, anhydrides, ethers, thiols, and aromatic nitro groups; the reaction can be extended to compounds containing the carbon to chlorine bond alpha to a carbon atom containing at least one hydrogen atom, it can be further dehydrochlorinated, e.g., by either heating to a temperature ranging from about 50° C. to about 300° C. or by reaction with a base selected, e.g., from alkali metal hydroxides and alkoxides.

Remarkably Selective Chlorination of Phthalic Anhydride and Its Monochlorinated Derivatives

The vapor-phase chlorination of phthalic anhydride 1 and its monochlorinated derivatives 2 and 3 in the temperature range from 390 to 600 deg C with elemental chlorine has been investigated and found to be highly selective.Thus, chlorination of 1 in the temperature range from 390 to 450 deg C was found to give high yields of monochlorinated products accompanied by only small amounts of dichlorination with a high degree of regioselectivity favoring the formation of 4-chlorophthalic anhydride.Chlorination of a 3-chlorophthalic anhydride 3 by this method has provided thefirst direct synthesis of 3,5-dichlorophthalic anhydride 7 from phthalic anhydride via chlorination.