117032-51-6

Basic information

• Product Name: 6-(N-TRIFLUOROACETYL)AMINOCAPROIC ACID N-SUCCINIMIDYL ESTER
• Synonyms: 6-(N-TRIFLUOROACETYL)AMINOCAPROIC ACID N-SUCCINIMIDYL ESTER;6-[(2,2,2-Trifluoroacetyl)aMino]hexanoic Acid 2,5-Dioxo-1-pyrrolidinyl Ester;N-[6-[(2,5-Dioxo-1-pyrrolidinyl)oxy]-6-oxohexyl]-2,2,2-trifluoro-acetaMide;N-[ε-trifluoroacetaMidocaproyloxy] succiniMide ester(TFCS);2,5-Dioxopyrrolidin-1-yl 6-(2,2,2-trifluoroacetamido)hexanoate
• CAS NO: 117032-51-6
• Molecular Formula: C₁₂H₁₅F₃N₂O₅
• Molecular Weight: 324.25
• Product Categories: Nitric Oxide Reagents;Cross Linking Reagents
• Mol File: 117032-51-6.mol

Chemical Properties

• Melting Point: 70-71°C
• Appearance: /
• Density: 1.39±0.1 g/cm3(Predicted)
• Storage Temp.: Hygroscopic, -20°C Freezer, Under Inert Atmosphere
• Solubility: Chloroform, Ethyl Acetate
• PKA: 11.38±0.46(Predicted)
• CAS DataBase Reference: 6-(N-TRIFLUOROACETYL)AMINOCAPROIC ACID N-SUCCINIMIDYL ESTER(CAS DataBase Reference)
• NIST Chemistry Reference: 6-(N-TRIFLUOROACETYL)AMINOCAPROIC ACID N-SUCCINIMIDYL ESTER(117032-51-6)
• EPA Substance Registry System: 6-(N-TRIFLUOROACETYL)AMINOCAPROIC ACID N-SUCCINIMIDYL ESTER(117032-51-6)

Safety Data

• Hazardous Substances Data: 117032-51-6(Hazardous Substances Data)

Usage

Uses

Used in Pharmaceutical Industry:
6-(N-TRIFLUOROACETYL)AMINOCAPROIC ACID N-SUCCINIMIDYL ESTER is used as a crosslinking agent for the development of novel drug delivery systems. Its amino reactive nature allows for the formation of stable covalent bonds with other molecules, enhancing the stability and bioavailability of pharmaceutical compounds.
Used in Biotechnology Industry:
In the biotechnology industry, 6-(N-TRIFLUOROACETYL)AMINOCAPROIC ACID N-SUCCINIMIDYL ESTER is used as a crosslinking agent for the modification of proteins and other biomolecules. Its ability to form covalent bonds with amino groups enables the creation of new bioconjugates with improved properties, such as increased stability, enhanced activity, or altered specificity.
Used in Research and Development:
6-(N-TRIFLUOROACETYL)AMINOCAPROIC ACID N-SUCCINIMIDYL ESTER is used as a research tool for studying protein-protein interactions, enzyme mechanisms, and other biological processes. Its amino reactive nature allows for the specific labeling or modification of proteins, providing valuable insights into their structure, function, and interactions with other molecules.
Used in Diagnostics:
6-(N-TRIFLUOROACETYL)AMINOCAPROIC ACID N-SUCCINIMIDYL ESTER is used in the development of diagnostic assays and tests. Its ability to form stable covalent bonds with amino groups can be exploited to create highly specific and sensitive detection methods for various analytes, including proteins, peptides, and small molecules.
Used in Material Science:
In the field of material science, 6-(N-TRIFLUOROACETYL)AMINOCAPROIC ACID N-SUCCINIMIDYL ESTER is used as a crosslinking agent for the development of novel materials with enhanced properties. Its ability to form covalent bonds with amino groups can be utilized to create materials with improved mechanical strength, thermal stability, or chemical resistance.
Used in Chemical Synthesis:
6-(N-TRIFLUOROACETYL)AMINOCAPROIC ACID N-SUCCINIMIDYL ESTER is used as a synthetic building block in the preparation of various complex organic molecules. Its unique reactivity and functional groups make it a valuable starting material for the synthesis of pharmaceuticals, agrochemicals, and other specialty chemicals.

Upstream product

• 6066-82-6 1-hydroxy-pyrrolidine-2,5-dione 
• 407-91-0 6-(trifluoroacetamido)hexanoic acid 
• 5672-89-9 N-trifluoroacetoxy succinimide 
• 60-32-2 6-aminohexanoic acid 
• 407-25-0 trifluoroacetic anhydride 
• 74124-79-1 di(succinimido) carbonate 

Downstream Products

• 166887-42-9 1-O-(4,4'-dimethoxytrityl)-4-N-(6-trifluoroacetamidocaproyl)-4-amino-1,3-butanediol 
• 125348-34-7 1-0-(Dimethoxytrityl)-3-N-(6-aminocaproyl)-Amino-1,2-Dihydroxypropane 
• 1446470-38-7 C₄₅H₄₆N₂O₆ 
• 1446470-39-8 C₅₄H₆₃N₄O₇P 
• 851912-61-3 (2S,4R)-1-(6-aminohexanoyl)-4-hydroxy-2-(4,4′-dimethoxytrityloxymethyl)pyrrolidine 

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