117174-46-6

Upstream product

• 53931-26-3 O-benzyl-3-dibromo-6,6-didesoxy-5,6-O-isopropylidene-1,2-α-D-xylo-hexeno-5-furannose-1,4 
• 90965-06-3 dimethyl 1-(1-diazo-2-oxopropyl)phosphonate 
• 23558-05-6 3-O-benzyl-1,2-O-isopropylidene-1,5-D-xylo-dialdofuranose 
• 63593-02-2 3-O-benzyl-1,2-O-isopropylidene-α-D-ribo-pentodialdo-1,4-furanose 
• 164213-49-4 (3aR,5R,6R,6aR)-6-Benzyloxy-5-(2,2-dibromo-vinyl)-2,2-dimethyl-tetrahydro-furo[2,3-d][1,3]dioxole 
• 558-13-4 carbon tetrabromide 
• 582-52-5 1,2:5,6-di-O-isopropylidene-α-D-glucofuranose 
• 18685-18-2 3-O-benzyl-1,2-5,6-O-diisopropylidene-α-D-glucofuranose 
• 100-39-0 benzyl bromide 
• 22529-61-9 (1R)-1-((3aR,6S,6aR)-6-(benzyloxy)-2,2-dimethyltetrahydrofuro(2,3-d)(1,3)dioxol-5-yl)ethane-1,2-diol 

Downstream Products

• 78942-98-0 (3-O-benzyl-5,6-didesoxy-1,2-O-isopropylidene-α-D-xylo-hex-5-ynofuranos-6-yl)phosphonate de diethyle 
• 934493-25-1 6-benzyloxy-2,2-dimethyl-5-(1-methylene-allyl)-tetrahydro-furo[2,3-d][1,3]dioxole 
• 1160926-69-1 (4R)-1,2-O-isopropylidene-3-O-benzyl-4-C-[(1-(2-nitrophenyl)-1H-1,2,3-triazol-4-yl)]-L-threofuranose 
• 1426233-53-5 C₂₉H₂₉NO₆S 
• 1426233-64-8 4S-4-C-(indol-2-yl)-3-O-benzyl-1,2-O-isopropylidene-α-L-threofuranoside 
• 117192-23-1 (E)-(R)-3-((3aR,5R,6R,6aR)-6-Benzyloxy-2,2-dimethyl-tetrahydro-furo[2,3-d][1,3]dioxol-5-yl)-1-((2R,3R,4S,5R,6R)-3,4,5-tris-benzyloxy-6-methoxy-tetrahydro-pyran-2-yl)-prop-2-en-1-ol 

Relevant academic research and scientific papers

A new versatile strategy for C-aryl glycosides

(Chemical Equation Presented) A versatile strategy involving a sequential intermolecular enyne metathesis of C-alkynyl glycosides with ethylene, Diels-Alder, and aromatization reactions is successfully developed to provide a range of C-aryl glycosides.

Construction of key building blocks towards the synthesis of cortistatins

This work reports the construction of key building blocks towards the synthesis of cortistatins; a family of steroidal alkaloids. Cortistatin A, being a primary target due to its superior biological properties over other congeners, has been prepared by two different synthetic routes. Synthesis of the precursor to the heavily substituted A-ring starting from d-glucose and construction of the DE-ring junction employing a Hajos-Parrish ketone as a chiral pool have been demonstrated. Efforts are underway to assemble these key fragments and build towards the total synthesis of cortistatin A.

Novel syntheses of aryl quinoxaline C-nucleoside analogs by mild and efficient three-component sequential reactions

Novel syntheses of C-nucleoside analogs with aryl quinoxalines as nucleobase surrogates have been accomplished by mild and efficient three-component sequential reactions in high yields with a wide scope of substrates. The mechanism was clarified by isolation of novel sugar 1,2-diketone derived from oxidation of the corresponding alkyne. the Partner Organisations 2014.

Application of an enyne metathesis/diels-alder cycloaddition sequence: A new versatile approach to the syntheses of C-Aryl glycosides and spiro- C-Aryl glycosides

An efficient approach for the synthesis of a variety of C-aryl and spiro- C-aryl glycosides is described. This diversity-oriented strategy employed here relies on a sequential enyne metathesis to generate the 1,3-diene moiety and Diels-Alder reaction with

Total synthesis of pachastrissamine (jaspine B) enantiomers from d-glucose

Synthesis of both enantiomers of pachastrissamine is described from a common chiral template. The stereoselective construction of the central tetrahydrofuran units was based on the pseudodesymmetrization of a pentodialdo-1,4-furanose derivative taking adv

Stereoselective Synthesis of Higher Sugar Dialdoses via Coupling of Terminal C-Atoms of Simple Monosaccharides

Different methods of the preparation of the precursors of higher carbon sugars via the coupling of monosaccharide sub-units are presented. The "economic" synthesis of such precursor is exemplified by the preparation of enone 11. Functionalization of the a

A NEW CONVENIENT APPROACH TO HIGHER SUGAR ALLYLIC ALCOHOLS

Allylic alcohol 4, a chiral synthon for the preparation of des-aza tunicamine (2), was obtained by two independent routes starting from either D-galactose or D-ribose derivatives.The selection of the starting material depends, therefore, only on its availability.The interchangeability of the synthetic routes is especially important when rare sugars have to be used in the synthesis.

Preparation de derives de sucres acetyleniques terminaux et d'acides ynuroniques par reaction de Wittig

The method described for the preparation of terminal acetylenic sugars presents two advantages over earlier procedures: no new asymmetric center is created and the chain can be extended by one or more C-atoms.The method also allows preparation of ynuronic