117184-95-9

Upstream product

• 541-50-4 2-acetoacetic acid 
• 104-88-1 4-chlorobenzaldehyde 
• 67-64-1 acetone 
• 108-22-5 Isopropenyl acetate 
• 123-42-2 4-Hydroxy-4-methyl-2-pentanone 
• 705933-31-9 2-[tris(pentafluorophenyl)silyloxy]propene 
• 14035-54-2 1,1-diphenyl-1-hydroxy-3-butanone 
• 1361966-87-1 4-(4-chlorophenyl)-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)butan-2-one 
• 3160-40-5 4-(4-chlorophenyl)-3-buten-2-one 
• 14506-33-3 1-(4-chlorophenyl)but-3-en-1-ol 
• 105104-40-3 Okahara's reagent 

Downstream Products

• 1204698-90-7 (1R,3R)-1-(4-chlorophenyl)-1,3-butanediol 
• 1204698-91-8 (1S,3R)-1-(4-chlorophenyl)-1,3-butanediol 
• 1204698-88-3 (1R,3S)-1-(4-chlorophenyl)-1,3-butanediol 
• 1204698-86-1 (1S,3S)-1-(4-chlorophenyl)-1,3-butanediol 
• 30626-03-0 (3E)-4-(4-chlorophenyl)-3-buten-2-one 

Relevant academic research and scientific papers

Au(I)-catalyzed cyclization of tert-butyl carbonates derived from homopropargyl alcohols: A catalytic alternative to cyclic enol carbonates

Au(I)-complexes catalyze cyclization of tert-butyl carbonates derived from a variety of homopropargyl alcohols. This procedure offers a catalytic alternative to stoichiometric Lewis acids for the preparation of a range of enol carbonates. Georg Thieme Verlag Stuttgart.

Catalytic aldol-transfer reactions with Al-alkoxide trapping

Al-BINOL catalyzed aldol-transfer reactions of aldehydes with diacetonealcohol conducted with Al-alkoxide trapping gave aldol adducts in good yields. The best yields were obtained with electron-rich aromatic aldehydes (e.g., 83% yield with 3,4,5-trimethoxybenzaldehyde).

Enhanced effect of mesoporous silica on base-catalyzed aldol reaction

Aldol reaction of 4-nitrobenzaldehyde with acetone gives 4-(4-nitrophenyl)-4-hydroxy-2-butanone in high yield in the presence of both secondary amine and mesoporous silica, whereas the yield is low in the absence of the mesoporous silica.

Convenient enol equivalents for catalytic aldol-transfer reactions

Solid crystalline and stable 1,1-diphenyl-1-hydroxy-3-butanone was shown to serve as an excellent precursor of the Al-enolate of acetone generated in situ for Al-BINOL catalyzed aldol-transfer reactions of aldehydes. The best yields were obtained with electron rich aromatic aldehydes and 2-pyridine carbaldehyde of which the latter gave 1-hydroxy-1-(2-pyridyl)-3-butanone in 79% yield.

A novel DNA-catalyzed aldol reaction

A novel DNA-catalyzed aldol reaction in water has been developed. This approach will be helpful in learning the role of DNA as a catalyst in the early stage during the development of life on earth. Georg Thieme Verlag Stuttgart.

Chitosan hydrogel: A green and recyclable biopolymer catalyst for aldol and Knoevenagel reactions

Chitosan hydrogel is efficiently utilized as an organocatalyst for aldol and Knoevenagel reactions, providing the products in high yields with a high chemoselectivity under biphasic conditions. The catalyst was recovered by simple filtration and reused several times without significant loss of activity. the Royal Society of Chemistry and the Centre National de la Recherche Scientifique 2006.

A selective direct aldol reaction in aqueous media catalyzed by zinc-proline

The Zn-proline complex is shown to catalyze the aldol reaction of acetone and a wide range of arenecarbaldehydes in aqueous media, accepting even deactivated arenecarbaldehydes such as methoxybenzaldehydes in good yields. Enantiomeric excesses of up to 56

Aldolase activity of serum albumins

Bovine and human serum albumins catalyze the aldol reaction of aromatic aldehyedes and acetone, with saturation kinetics and moderate and opposite enantioselectivity. The reaction occurs at the binding site in domain IIa, and is inhibited by warfarin. Kin

Biomass waste-derived recyclable heterogeneous catalyst for aqueous aldol reaction and depolymerization of PET waste

In this work, we discuss the valorization of biomass waste-derived orange peel ash (OPA) by exploring its applicability as a heterogeneous catalyst in aqueous aldol reactions and demonstrating its versatility by promoting the methanolysis of poly(ethylene terephthalate) (PET) waste. The catalyst was characterized using Fourier-transform infrared spectroscopy (FT-IR), Brunauer-Emmett-Teller (BET) analysis, X-ray powder diffraction (XRD), X-ray fluorescence (XRF), energy dispersive X-ray (EDX) spectroscopy, scanning electron microscopy (SEM), transmission electron microscopy (TEM), X-ray photoelectron spectroscopy (XPS), and thermal gravimetric analysis (TGA) to decode its chemical composition. The aldol reactions were carried out at ambient temperature in the presence of water as a solvent. PET depolymerization was performed in an autoclave for 1 h using only 6% w/w OPA. The catalyst was recovered and reused in both the reactions for up to four successive cycles with minimal loss in the catalytic activity. The use of OPA as a cost-free, eco-friendly and effective recyclable catalyst enables a greener route for C-C bond formation and PET waste recycling.

Cellulosic CuI Nanoparticles as a Heterogeneous, Recyclable Catalyst for the Borylation of α,β-Unsaturated Acceptors in Aqueous Media

Abstract: We have demonstrated that cellulosic CuI nanoparticles could perform as an efficient heterogeneous catalyst for the synthesis of useful organoboron compounds. Desired β-borylation products were all obtained in good to excellent yields under mild