14506-33-3

Usage

Uses

Used in Pharmaceutical Industry:
1-(4-Chlorophenyl)-3-buten-1-ol 97 is used as a starting material for the synthesis of pharmaceuticals, leveraging its reactive functional groups to form a variety of biologically active molecules. Its presence in the synthesis process is crucial for developing new drugs with potential therapeutic applications.
Used in Agrochemical Industry:
In the agrochemical sector, 1-(4-Chlorophenyl)-3-buten-1-ol 97 serves as an intermediate in the production of various agrochemicals. Its chemical properties make it suitable for the development of compounds that can be used in crop protection and other agricultural applications, contributing to enhanced crop yields and protection against pests.
Used in Organic Synthesis:
1-(4-Chlorophenyl)-3-buten-1-ol 97 is utilized as a reagent in organic synthesis, where its unique structure facilitates a range of chemical reactions. This versatility allows for the creation of diverse organic compounds for various applications, highlighting its importance in the field of organic chemistry.
Used in Medicinal Chemistry Research:
1-(4-CHLOROPHENYL)-3-BUTEN-1-OL 97 holds potential applications in the field of medicinal chemistry, where it can be explored for its possible biological activities. Researchers and professionals in the chemical industry value 1-(4-Chlorophenyl)-3-buten-1-ol 97 for its ability to contribute to the discovery and development of novel therapeutic agents.

InChI:InChI=1/C10H11ClO/c1-2-3-10(12)8-4-6-9(11)7-5-8/h2,4-7,10,12H,1,3H2

Upstream product

• 104-88-1 4-chlorobenzaldehyde 
• 106-95-6 allyl bromide 
• 13891-90-2 4-(p-Chlorphenyl)-4-(triethylstannyloxy)-but-1-en 
• 13911-49-4 allyltriethyllead 
• 627-15-6 1,3-dibromopropene 
• 1793-91-5 tetraallylgermanium 
• 107-05-1 3-chloroprop-1-ene 
• 7393-43-3 tetraallyl tin 
• 134988-30-0 benzyldibutyltelluronium bromide 
• 556-56-9 allyl iodid 
• 17381-88-3 Diallyltin(IV) dibromide 
• 107-18-6 allyl alcohol 
• 36971-15-0 3-isopropyl-2-methyl-hex-5-en-3-ol 
• 2622-05-1 allylmagnesium bromide 

Downstream Products

• 32271-56-0 (E)-4-(4-chlorophenyl)but-3-en-2-ol 
• 14506-33-3 (S)-1-(4-chlorophenyl)-but-3-en-1-ol 
• 1027026-75-0 C₁₅H₂₁ClOSi 
• 1094999-04-8 C₁₃H₁₄BrClO 
• 1026779-10-1 (E)-1-chloro-4-(3-methoxybut-1-enyl)benzene 

Relevant academic research and scientific papers

AgOAc-catalyzed aldehyde allylation using allyldimethyl(2-pyridyl)silane

Silver salts having relatively strong Ag-O bond were found to promote the allylation of aldehydes with allyldimethyl(2-pyridyl)silane. Catalytic allylation is also possible when AgOAc was employed. A novel cooperative activation of allyl(2-pyridyl)silane has been implicated from several control experiments.

Bismuth(III) Chloride-Aluminium-promoted Allylation of Aldehydes to Homoallylic Alcohols in Aqueous Solvent

In the presence of bismuth(III)chloride-metallic aluminium, allylic halides have been found to react with aldehydes at room temperature in tetrahydrofuran-water to afford the corresponding homoallylic alcohols in high yields.

Aerosol-spraying synthesis of periodic mesoporous organometalsilica spheres with chamber cavities as active and reusable catalysts in aqueous organic reactions

Organometal-bridged periodic mesoporous catalysts with uniform spheres containing cavities in chambers were synthesized by rapid aerosol-spray assisted co-condensation between organometallic silane and tetraethoxysilane (TEOS) in the presence of cetyltrimethyl ammonium bromide (CTAB) and NaCl double templates. The as-prepared M-PPh2-PMO(H) catalysts (M = Pd 2+, Rh+ and Ru2+) were used in various water-medium organic reactions with the aim of diminishing environmental pollution from organic solvents. These catalysts exhibited high catalytic activities and selectivities owing to the high surface area, the uniform distribution of active sites, the ordered mesoporous channels and especially, the cavities as microreactors which facilitated the diffusion and adsorption of organic reactants. Meanwhile, they also displayed strong durability and could be used repeatedly owing to the organometals incorporated into silica walls and the presence of chamber cavities which could effectively protect the ordered mesoporous structure from damage and also inhibit the leaching of active sites.

Lanthanide(II) Iodide Catalysed Photochemical Allylation of Aldehydes with Allylic Halides

Lanthanide(II) iodides such as SmI2 and YbI2 show high catalytic activity for the photochemical allylation of aldehydes with allylic halides to give the corresponding homoallylic alcohols.

Periodic mesoporous organosilica grafted palladium organometallic complex: Efficient heterogeneous catalyst for water-medium organic reactions

Water-medium organic reactions were studied over periodic mesoporous silica (PMO) containing Pd(II) organometallic complex. This heterogeneous catalyst was achieved by Pd(II) compound coordinated with the PPh2-ligand onto the pore surface of ph

Indium(I)/CuFe2O4 Reagent for Allylation of Carbonyls and Epoxide Rearranged Carbonyls

Abstract: Indium(I)/CuFe2O4 reagent forcarbonyl allylation and epoxide rearranged carbonyl allylation is proposed forformation of homoallylic alcohols. The In(I) reagent in combination withcatalytic amount of CuFe2O4support in situ formation of nucleophilicallylic indium from allyl halide in THF medium. Nucleophilic allylic indiumspecies react with carbonyls to form homoallyl alcohols in good to excellentyields. Under the presented reaction conditions arylepoxides undergo smoothrearrangement into aldehydes that are also allylated with formation of homoallylalcohols. The process is highly efficient and tolerates different functionalgroups.

Barbier-type addition of alkyl halides to aldehydes promoted by pentacarbonyliron

The yield and structure of products of the Barbier-type addition of alkyl halides (perfluorobutyl iodide, allyl bromide, allyl iodide, and hexyl iodide) to para-substituted benzaldehydes in the presence of pentacarbonyliron are essentially determined, on the one hand, by the ability of alkyl halide to be reduced to carbanion and, on the other, by the electrophilicity of the aldehyde reaction center which in turn depends on the nature of para-substituent in the aromatic ring.

A novel indium-boron amorphous alloy mediator for barbier-type carbonyl allylation in aqueous medium

A novel indium-boron (In-B) amorphous alloy was prepared by chemical reduction of indi- um(III) ions [In3+] with borohydride [BH 4-] in aqueous solution and was applied to the water-medium Barbier-type allylation reactions

Nitrogen-Doped Carbon-Incarcerated Zinc Electrodes as Heterogeneous Catalysts for Electrochemical Allylation of Carbonyl Compounds

Electrochemical allylation reactions of carbonyl compounds using cathodes prepared from nitrogen-doped carbon (NDC)-incarcerated zinc catalysts have been developed. A range of aldehydes and ketones afforded the desired allylic alcohols in high yields with 10 mol % zinc leaching, and the heterogeneous nature of the active species was suggested. Compared with bulk zinc electrodes, NDC-stabilized zinc nanoparticle species were compatible with a broader range of heteroaromatic substrates and enabled the use of an undivided cell.

Visible Light-Promoted Recyclable Carbon Nitride-Catalyzed Dioxygenation of β,γ-Unsaturated Oximes

A visible-light-induced dioxygenation of β,γ-unsaturated oximes for the synthesis of diverse useful isoxazolines bearing a hydroxyl moiety was developed by employing graphitic carbon nitride (g-C3N4) as a heterogeneous photocatalyst under an air atmosphere. Noted that, the eminent advantages of this metal-free protocol include step economy, easy operation, a recyclable photocatalyst, external reductant-/oxidant-free and mild reaction conditions. Additionally, mechanistic studies indicated hydroxyl radical was generated under the photocatalysis of g-C3N4.