117251-96-4

Upstream product

• 85846-80-6 5-O-benzyl-2,3-O-isopropylidene-D-ribono-1,4-lactone 
• 34939-91-8 dimethyl lithiomethylphosphonate 
• 100-39-0 benzyl bromide 
• 30725-00-9 2,3-O-isopropylidene-D-ribonic-γ-lactone 
• 85846-80-6 (-)-5-O-benzyl-2,3-O-isopropylidene-D-ribono-1,4-lactone 
• 756-79-6 dimethyl methane phosphonate 

Downstream Products

• 89291-71-4 (3R,4R)-(-)-6-O-benzyl-1-deoxy-1-(dimethylphosphono)-3,4-O-isopropylidene-D-ribo-hexulose 
• 89291-74-7 (3R,4R)-(-)-6-O-benzyl-1-deoxy-1-(dimethylphosphono)-3,4-O-isopropylidene-D-erythro-2,5-hexodiulose 
• 89291-81-6 (-)-9-<(1R,4R,5S)-3-<(benzyloxy)methyl>-4,5-O-isopropylidene-2-cyclopenten-1-yl>-6-chloropurine 
• 89291-82-7 (-)-9-<(1R,4R,5S)-3-<(benzyloxy)methyl>-4,5-O-isopropylidene-2-cyclopenten-1-yl>adenine 
• 100806-47-1 (1S,4R,5S)-(-)-3-<(benzyloxy)methyl>-4,5-O-isopropylidene-2-cyclopenten-1-ol p-toluenesulfonate 
• 117307-62-7 (3aR,6aR)-6-Benzyloxymethyl-2,2-dimethyl-4,6a-dihydro-3aH-cyclopenta[d][1,3]dioxol-4-one 
• 89291-76-9 (1S,4R,5S)-(-)-3-<(benzyloxy)methyl>-4,5-O-isopropylidene-2-cyclopenten-1-ol 
• 89291-80-5 (1R,4R,5S)-(-)-1-<(5-amino-6-chloropyrimidinyl)amino>-3-<(benzyloxy)methyl>-4,5-O-isopropylidene-2-cyclopentene 
• 89291-78-1 (1R,4R,5S)-(-)-1-azido-3-<(benzyloxy)methyl>-4,5-O-isopropylidene-2-cyclopentene 
• 89291-79-2 (1R,4R,5S)-(-)-1-amino-3-<(benzyloxy)methyl>-4,5-O-isopropylidene-2-cyclopentene 
• 89291-77-0 (1S,4R,5S)-(-)-3-<(benzyloxy)methyl>-4,5-O-isopropylidene-2-cyclopenten-1-ol methanesulfonate 
• 89291-75-8 (3aR*,6aR*)-6-Benzyloxymethyl-2,2-dimethyl-4,6a-dihydro-3aH-cyclopenta[d][1,3]dioxol-4-one 
• 72877-50-0 neplanocin A 
• 89291-71-4 {2-[(4S,5R)-5-((R)-2-Benzyloxy-1-hydroxy-ethyl)-2,2-dimethyl-[1,3]dioxolan-4-yl]-2-oxo-ethyl}-phosphonic acid dimethyl ester 

Relevant academic research and scientific papers

TOTAL SYNTHESIS OF (-)-NEPLANOCIN A

A total synthesis of (-)-neplanocin A has been accomplished in 15 steps starting from the readily available D-(+)-ribonic acid γ-lactone.

CONVENIENT OXIDATIONS OF CARBOHYDRATE DERIVED LACTOLS AND OF ε-HYDROXY-β-KETOPHOSPHONATES

Convenient oxidation of carbohydrate derived lactols to lactones as well as the oxidation of ε-hydroxy-β-ketophosphonates to their corresponding β,ε-diketophosphonates can be performed with the Dess-Martin periodinane in high yields.

Total Synthesis of (-)-Neplanocin A

An efficient synthesis of neplanocin A, which is easily adaptable for the preparation of other cyclopentenyl containing nucleoside isosteres, has been developed.This enantioselective synthesis provides control of two of the three chiral centers of neplano