1173102-81-2Relevant academic research and scientific papers
Structure-based molecular design, synthesis, and in vivo anti-inflammatory activity of pyridazinone derivatives as nonclassic COX-2 inhibitors
Abouzid, Khaled A. M.,Khalil, Nadia A.,Ahmed, Eman M.,El-Latif, Hekmat A. Abd,El-Araby, Moustafa E.
, p. 629 - 642 (2011/12/02)
A scaffold with bicyclic core carrying pyridazinone moiety, which exhibited potent in vivo anti-inflammatory activities, was introduced in this article. The design of these compounds was assisted by docking and superposition experiments on cyclooxygenase-
