35990-93-3

Upstream product

• 123-76-2 levulinic acid 
• 123-11-5 4-methoxy-benzaldehyde 
• 87722-15-4 C₁₃H₁₄O₄ 

Downstream Products

• 95605-93-9 4-methyl-6-(α-p-methoxystyryl)pyridazin-3(2H)-one 
• 83516-67-0 6-[(E)-2-(4-Methoxy-phenyl)-vinyl]-2H-pyridazin-3-one 
• 1173102-84-5 6-[2-(4-methoxyphenyl)ethyl-1,2-dibromo]pyridazin-3(2H)-one 
• 1173102-89-0 2-(4-methoxyphenyl)-3-(6-oxo-1,6-dihydropyridazin-3-yl)-1,2,3,4-tetrahydroquinoxaline 
• 1173102-81-2 2-(4-methoxyphenyl)-3-(6-oxo-1,6-dihydropyridazin-3-yl)quinoxaline 
• 1173102-93-6 6-(2-(4-methoxyphenyl)-1-bromoethyl)pyridazin-3-(2H)-one 
• 87563-71-1 6-(α-p-methoxystyryl)pyridazin-3(2H)-one 
• 83516-77-2 2-Morpholinomethyl-6-(4-methoxy-α-styryl)pyridazin-3(2H)-one 
• 83516-80-7 4-Benzyl-6-[(E)-2-(4-methoxy-phenyl)-vinyl]-2H-pyridazin-3-one 
• 83516-73-8 6-[(E)-2-(4-Methoxy-phenyl)-vinyl]-2-methyl-2H-pyridazin-3-one 
• 83516-76-1 3-Chloro-6-[(E)-2-(4-methoxy-phenyl)-vinyl]-pyridazine 

Relevant academic research and scientific papers

Synthesis and anti-inflammatory activity of novel pyridazine and pyridazinone derivatives as non-ulcerogenic agents

Herein, we report the synthesis and pharmacological properties of several series of pyridazine and pyridazinone derivatives. All the synthesized compounds were tested, in vivo, for their anti-inflammatory and ulcerogenic properties against indomethacin, a

Structure-based molecular design, synthesis, and in vivo anti-inflammatory activity of pyridazinone derivatives as nonclassic COX-2 inhibitors

A scaffold with bicyclic core carrying pyridazinone moiety, which exhibited potent in vivo anti-inflammatory activities, was introduced in this article. The design of these compounds was assisted by docking and superposition experiments on cyclooxygenase-