117471-52-0Relevant academic research and scientific papers
Monosubstitution of Symmetric Piperazine-2,5-dione Derivatives
Badran, Terry W.,Easton, Christopher J.
, p. 1455 - 1459 (2007/10/02)
Bromination and methanolysis of derivatives of glycine anhydride affords the corresponding 3-bromo- and 3-methoxy-substituted piperazine-2,5-dione derivatives in a simple one-pot procedure.
Versatile New Approach to the Synthesis of Monosubstituted and Bicyclic Piperazine-2,5-diones: Unusual in Situ Generation and Enolate Addition to a Cumulene
Williams, Robert M.,Kwast, Andrzej
, p. 5785 - 5787 (2007/10/02)
Dichloroacetyl chloride condenses with glycinamide 9 to furnish the versatile precursor 10, which cyclizes to the mono (ether) substituted piperazinediones 11 upon treatment with alkoxides.A new intramolecular enolate C-C bond-forming cyclization from the
