117516-63-9

Basic information

• Product Name: 2-(2,2-Diethoxyethoxy)toluene
• Synonyms: 2-(2,2-Diethoxyethoxy)toluene;1-(2,2-Diethoxy-ethoxy)-2-Methyl-benzene
• CAS NO: 117516-63-9
• Molecular Formula: C₁₃H₂₀O₃
• Molecular Weight: 224.2961
• Mol File: 117516-63-9.mol
• Article Data: 11

Chemical Properties

• Boiling Point: 306.7±37.0 °C(Predicted)
• Appearance: /
• Density: 0.995±0.06 g/cm3(Predicted)
• CAS DataBase Reference: 2-(2,2-Diethoxyethoxy)toluene(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(2,2-Diethoxyethoxy)toluene(117516-63-9)
• EPA Substance Registry System: 2-(2,2-Diethoxyethoxy)toluene(117516-63-9)

Safety Data

• Hazardous Substances Data: 117516-63-9(Hazardous Substances Data)

Usage

Chemical Family

The compound belongs to the toluene family.

Physical State

It is a colorless liquid.

Odor

The compound has a characteristic sweet odor.

Solubility

It is soluble in organic solvents.

Usage

The compound is primarily used as a solvent and in the production of various chemical products.

Applications

It is commonly used as a component in coatings, adhesives, and inks, as well as in the production of fragrances and flavors.

Importance

The compound serves as a valuable intermediate in the synthesis of pharmaceuticals and other fine chemicals, making it an important chemical in various industries.

Upstream product

• 95-48-7 ortho-cresol 
• 621-62-5 chloroacetaldehyde diethyl acetal 
• 2032-35-1 Bromoacetaldehyde diethyl acetal 
• 4549-72-8 sodium o-cresolate 

Downstream Products

• 1027281-66-8 4-[4-(7-methyl-benzofuran-2-yl)-4-oxo-butyryl]-benzoic acid methyl ester 
• 1026278-52-3 4-[5-(7-methyl-benzofuran-2-yl)-1H-pyrrol-2-yl]-benzoic acid methyl ester 
• 57897-70-8 7-methyl-2-benzofurancarboxaldehyde 
• 17059-52-8 7-methylbenzofuran 
• 103195-89-7 2-(o-tolyloxymethyl)thiazolidine 
• 41964-08-3 5-o-tolyloxy-1H-pyrimidin-2-one 

Relevant articles and documents

Regioselective tandem dimethylsulfonium methylide addition - Eliminative olefination of diendioates: A novel route to 1,3-butadien-2-ylmalonates

The appropriate choice of dimethylsulfonium methylide generation conditions enables the highly regioselective tandem ylide addition-eliminative olefination to 1,3-dienedioates providing 1,3-butadien-2-ylmalonates, a novel class of 2-substituted 1,3-dienes suitable for quick assembly of precursors for type 2 intramolecular Diels-Alder reactions.

Palladium-Catalyzed Regioselective C-2 Arylation of Benzofurans with N′-Acyl Arylhydrazines

A novel ligand-free palladium-catalyzed C-2 arylation of benzofurans has been developed using N′-acyl arylhydrazines as the coupling partners and TEMPO as an oxidant. This protocol features a wide functional-group tolerance and highly regioselective products with good to excellent yields.

Palladium-Catalyzed Dearomatizing Difunctionalization of Indoles and Benzofurans

A palladium-catalyzed dearomatizing difunctionalization of N-Boc-indoles and benzofurans to give tricyclic indolines and 2,3-dihydrobenzofurans with a fully substituted carbon center is described. Product formation occurs under mild conditions at room temperature with commercially available aryl boronic acids and 2,2,6,6-tetramethylpiperidine-1-oxyl (TEMPO) as a mild oxidant in good yields. 2-Carboxyalkyl-substituted indoles and benzofurans react under Pd-catalysis with aryl boronic acids and TEMPO through dearomatizing arylation/cyclization to the corresponding indolines and dihydrobenzofurans containing a lactone moiety bearing a fully substituted carbon center.