17059-52-8Relevant articles and documents
-
Elvidge,Foster
, p. 590,592 (1963)
-
Preparation method of benzofuran compound
-
Paragraph 0106-0109, (2019/04/04)
The invention relates to a preparation method of a benzofuran compound. The preparation method comprises the following steps: putting a furan compound, acetic acid and a Lewis acid catalyst in a reaction vessel, reacting for 0.5-24 h at 80-160 DEG C, and separating and purifying to obtain the benzofuran compound. According to the preparation method provided by the invention, the furan compound isused as a reaction raw material, an acetic acid water solution is used as a solvent, Lewis acid is used as a catalyst, and at a mild reaction temperature (80-160 DEG C), the benzofuran compound is directly obtained through one-step reaction. The preparation method provided by the invention can synthesize the benzofuran compound with a corresponding structure and functional groups based on the structure and functional groups of the furan compound as a raw material, the raw material components are simple , and the process is convenient to operate; wherein the selectivity of the obtained benzofuran is as high as 99% in the process of synthesizing benzofuran by using furan, so that the method has industrial application prospects.
Palladium-Catalyzed Regioselective C-2 Arylation of Benzofurans with N′-Acyl Arylhydrazines
Cao, Jun,Chen, Zi-Li,Li, Shu-Min,Zhu, Gao-Feng,Yang, Yuan-Yong,Wang, Cong,Chen, Wen-Zhang,Wang, Jian-Ta,Zhang, Ji-Quan,Tang, Lei
, p. 2774 - 2779 (2018/06/21)
A novel ligand-free palladium-catalyzed C-2 arylation of benzofurans has been developed using N′-acyl arylhydrazines as the coupling partners and TEMPO as an oxidant. This protocol features a wide functional-group tolerance and highly regioselective products with good to excellent yields.
A Pincer Ruthenium Complex for Regioselective C-H Silylation of Heteroarenes
Fang, Huaquan,Guo, Le,Zhang, Yuxuan,Yao, Wubing,Huang, Zheng
, p. 5624 - 5627 (2016/11/17)
A pincer Ru(II) catalyst for the highly efficient undirected silylation of O- and S-heteroarenes with (TMSO)2MeSiH and Et3SiH is described, producing heteroarylsilanes with exclusive C2-regioselectivity, good functional-group tolerance, and high turnover numbers (up to 1960). The synthetic utility of the silylated products is demonstrated by Pd-catalyzed Hiyama-Denmark cross-coupling under mild conditions. One-pot, two-step silylation and coupling procedures have been also developed.