117575-36-7Relevant academic research and scientific papers
Synthesis of 2-aryloxy- and 2-arylalkoxy-1-(2-piperidyl)ethanols
Mauleon,Dolors Pujol,Minguillon,Miquel
, p. 693 - 699 (2007/10/02)
The preparation and separation of diastereomeric pairs of a series of 2-aryloxy- and 2-arylalkoxy-1-(2-piperidyl)ethanols is reported. The erythro aminoalcohols were converted into threo isomers by thionyl chloride treatment of their N-acetyl derivatives
Synthesis and β-adrenergic antagonism of 2-(aryloxy)-1-(2-piperidyl)ethanols
Mauleon,Pujol,Rosell
, p. 2122 - 2126 (2007/10/02)
A series of erythro- and threo-2-(aryloxy)-1-(2-piperidyl)ethanol derivatives (3) was synthesized from 2-(2-oxiranyl)pyridine for evaluation as β-antagonists. Most compounds displayed high competitive β-blocking potency, but they lacked significant β
