55967-94-7

Basic information

• Product Name: Pyridine, 2-oxiranyl-
• CAS NO: 55967-94-7
• Molecular Formula: C7H7NO
• Molecular Weight: 121.139
• Mol File: 55967-94-7.mol
• Article Data: 12

Chemical Properties

• CAS DataBase Reference: Pyridine, 2-oxiranyl-(CAS DataBase Reference)
• NIST Chemistry Reference: Pyridine, 2-oxiranyl-(55967-94-7)
• EPA Substance Registry System: Pyridine, 2-oxiranyl-(55967-94-7)

Safety Data

• Hazardous Substances Data: 55967-94-7(Hazardous Substances Data)

Upstream product

• 100-69-6 2-vinylpyridine 
• 1121-60-4 pyridine-2-carbaldehyde 
• 3086-29-1 trimethylsulfonium chloride 
• 70775-39-2 dimethylsulfoxonium methylide 
• 1774-47-6 trimethylsulfoxonium iodide 
• 55967-97-0 2-bromo-1-(pyridin-2-yl)ethan-1-ol 
• 593-71-5 Chloroiodomethane 
• 2181-44-4 trimethylsulfonium methylsulfate 

Downstream Products

• 115462-40-3 2-(benzyloxy)-1-(2-pyridyl)ethanol 
• 237081-53-7 (S)-2-(oxiran-2-yl)pyridine 
• 308366-26-9 (1R)-1-(pyridin-2-yl)ethane-1,2-diol 
• 375367-57-0 (+/-)-2-Phenylsulfanyl-1-(2-pyridinyl)ethanol 
• 93-56-1 phenylethane 1,2-diol 
• 73908-30-2 (-)-(R)-2-Pyridylethylene oxide 
• 115462-70-9 1-{(R)-2-[(R)-1-Hydroxy-2-(3-phenyl-propoxy)-ethyl]-piperidin-1-yl}-ethanone 
• 115462-71-0 1-{(R)-2-[(S)-1-Hydroxy-2-(3-phenyl-propoxy)-ethyl]-piperidin-1-yl}-ethanone 
• 115462-66-3 1-[(R)-2-((R)-1-Hydroxy-2-p-tolyloxy-ethyl)-piperidin-1-yl]-ethanone 
• 115462-67-4 1-[(R)-2-((S)-1-Hydroxy-2-p-tolyloxy-ethyl)-piperidin-1-yl]-ethanone 
• 115462-64-1 1-[(R)-2-((R)-1-Hydroxy-2-m-tolyloxy-ethyl)-piperidin-1-yl]-ethanone 
• 115462-65-2 1-[(R)-2-((S)-1-Hydroxy-2-m-tolyloxy-ethyl)-piperidin-1-yl]-ethanone 
• 115462-68-5 1-[(R)-2-((R)-2-Benzyloxy-1-hydroxy-ethyl)-piperidin-1-yl]-ethanone 
• 115462-69-6 1-[(R)-2-((S)-2-Benzyloxy-1-hydroxy-ethyl)-piperidin-1-yl]-ethanone 

Relevant articles and documents

Organomagnesium Based Flash Chemistry: Continuous Flow Generation and Utilization of Halomethylmagnesium Intermediates

The generation of highly unstable chloromethylmagnesium chloride in a continuous flow reactor and its reaction with aldehydes and ketones is reported. With this strategy, chlorohydrins and epoxides were synthesized within a total residence time of only 2.6 s. The outcome of the reaction can be tuned by simply using either a basic or an acidic quench. Very good to excellent isolated yields, up to 97%, have been obtained for most cases (30 examples).

Manganese(II)/Picolinic Acid Catalyst System for Epoxidation of Olefins

An in situ generated catalyst system based on Mn(CF3SO3)2, picolinic acid, and peracetic acid converts an extensive scope of olefins to their epoxides at 0 °C in 5 min, with remarkable oxidant efficiency and no evidence of radical behavior. Competition experiments indicate an electrophilic active oxidant, proposed to be a high-valent Mn = O species. Ligand exploration suggests a general ligand sphere motif contributes to effective oxidation. The method is underscored by its simplicity and use of inexpensive reagents to quickly access high value-added products.

DNA-based hydrolytic kinetic resolution of epoxides

DNA-bound copper(II) complexes serve as catalysts for the hydrolytic kinetic resolution of 2-pyridyloxiranes in water. Selectivity factors of up to 2.7 were achieved, indicating a chirality transfer of DNA to epoxides via a coordinated metal ion.