117677-83-5Relevant academic research and scientific papers
Synthesis of a 'reverse ester' analogue of 1,2-sn-diglycerides from (S)-1,2-di-O-isoprophylideneglycerol; efficient, stereospecific nucleophilic displacement via a triflate at glycerol C-2
Golding, Bernard T.,Griffin, Alice L.,Robinson, David H.
, p. 6459 - 6462 (2007/10/02)
An optically pure glyceride analogue in which the 2-O-ester grouping has been reversed was efficiently synthesised from (S)-di-O-isopropylideneglycerol by a sequence that featured an SN 2 displacement by the anion of diethyl malonate on a protected glycerol 2-O-triflate.
The Chemistry of L-Ascorbic and D-Isoascorbic Acids. 2. R and S Glyceraldehydes from a Common Intermediate
Mikkilineni, Amarendra B.,Kumar, Praveen,Abushanab, Elie
, p. 6005 - 6009 (2007/10/02)
(R)- and (S)-glyceraldehyde and glycerol derivatives have been prepared from (2R,3S)-1,2-O-isopropylidenebutane-1,2,3,4-tetrol. (2R,3S)- and (2S,3S)-1,2-O-benzylidenebutane-1,2,3,4-tetrol have been prepared and cleaved to give (R)- and (S)-1,2-O-benzylideneglyceraldehydes and -glycerols.The conservation of chirality and conversion to PAF analogues are also demonstrated.
