117718-84-0

Usage

Uses

Used in Pharmaceutical Industry:
6-bromoimidazo[1,2-a]pyrazin-8-amine is used as a key intermediate in the synthesis of pharmaceutical drugs for its ability to be incorporated into the molecular structures of potential therapeutic agents. Its unique chemical properties allow it to contribute to the development of novel compounds with specific biological activities.
Used in Medicinal Chemistry Research:
As a research tool, 6-bromoimidazo[1,2-a]pyrazin-8-amine is utilized in medicinal chemistry to explore its interactions with biological targets, aiding in the understanding of disease mechanisms and the discovery of new drug candidates.
Used in Organic Synthesis:
6-bromoimidazo[1,2-a]pyrazin-8-amine is employed as a versatile building block in organic synthesis, enabling the creation of a diverse range of organic compounds for various applications, including but not limited to pharmaceuticals, agrochemicals, and materials science.
Used in Chemical Biology Studies:
Due to its distinctive structure, 6-bromoimidazo[1,2-a]pyrazin-8-amine serves as a probe in chemical biology, facilitating investigations into the mechanisms of biological processes and the identification of new bioactive molecules.

InChI:InChI=1/C6H5BrN4/c7-4-3-11-2-1-9-6(11)5(8)10-4/h1-3H,(H2,8,10)

Upstream product

• 63744-22-9 6,8-dibromoimidazo[1,2-a]pyrazine 

Downstream Products

• 1421425-95-7 C₂₇H₂₅N₉O 
• 117718-88-4 imidazo[1,2-a]pyrazin-8-amine 

Relevant academic research and scientific papers

IMIDAZO[1,2-A]PYRAZINE MODULATORS OF THE ADENOSINE A2A RECEPTOR

The present invention relates to the compound of formula (I) and salts, stereoisomers, tautomers, isotopologues,or N-oxides thereof. The present invention is further concerned with the use of such a compound or salt, stereoisomer, tautomer, isotopologues,or N-oxide thereof as medicament and a pharmaceutical composition comprising said compound.

Novel imidazopyrazines as cyclin dependent kinase inhibitors

In its many embodiments, the present invention provides a novel class of imidazo[1,2-a]pyrazine compounds as inhibitors of cyclin dependent kinases, methods of preparing such compounds, pharmaceutical compositions containing one or more such compounds, me

6-ARYL-IMIDAZO[1,2-a]PYRAZIN-8-YLAMINES, METHOD OF MAKING, AND METHOD OF USE THEREOF

A composition comprises a compound of Formula (I) the pharmaceutically acceptable salts, hydrates, solvates, crystal forms, diastereomers, prodrugs, or mixtures thereof. The composition is of particular utility in the treatment of kinase-implicated disord

Synthesis and Antibronchospastic Activity of 8-Alkoxy- and 8-(Alkylamino)imidazopyrazines

Theophylline still occupies a dominant place in asthma therapy.Unfortunatly its adverse central nervous system (CNS) stimulant effects can dramatically limit its use, and adjustments in the dosage are often needed.We have synthesized a new series of imidazopyrazine derivatives which are much more potent bronchodilators than theophylline in vivo and do not exhibit the CNS stimulatory profile.In vitro studies on isolated rat uterus and guinea pig trachea confirm the high potentialities of these derivatives. 6-Bromo-8-(methylamino)imidazopyrazine-3-carbonitrile (23) is identified as the most potent compound of the series.As i n the case of theophylline, phosphodiesterase inhibition appears unlikely to be the unique mechanism of the action of this series of heterocycles.