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1177425-23-8

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1177425-23-8 Usage

General Description

Fmoc-Arg(MIS)-OH is a chemical compound used in peptide synthesis. It is a derivative of arginine that is protected with the Fmoc (9-fluorenylmethyloxycarbonyl) group and modified with the MIS (m-isopropylbenzylsulphonyl) group. Fmoc-Arg(MIS)-OH is commonly used as a building block for the synthesis of peptides and proteins, as the Fmoc group can be easily removed under mild acidic conditions to expose the amino group for further reactions while the MIS group protects the arginine side chain. Fmoc-Arg(MIS)-OH is often used in solid-phase peptide synthesis and has applications in pharmaceutical research and drug development.

Check Digit Verification of cas no

The CAS Registry Mumber 1177425-23-8 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,1,7,7,4,2 and 5 respectively; the second part has 2 digits, 2 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 1177425-23:
(9*1)+(8*1)+(7*7)+(6*7)+(5*4)+(4*2)+(3*5)+(2*2)+(1*3)=158
158 % 10 = 8
So 1177425-23-8 is a valid CAS Registry Number.

1177425-23-8Relevant articles and documents

METHOD FOR THE PREPARATION OF H-ARG (MIS) -OH

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, (2018/04/21)

The invention discloses a method for the preparation of N-omega- (1, 2-dimethylindole-3-sulfonyl) -L-arginine and its derivatives using L-ornithine.

INDOLESULFONYL PROTECTING GROUPS FOR PROTECTION OF GUANIDINO AND AMINO GROUPS

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Page/Page column 21-22, (2010/01/29)

The invention relates to indolesulfonyl halogenides which are useful for the protection of organic compounds comprising at least one guanidino moiety and/or at least one amino group. The invention further relates to a process for their preparation and their use as protecting reagents. The invention also relates to the process for the protecting reaction and to the protected compounds thereof.

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