118237-88-0

Basic information

• Product Name: 2-Cyclopentene-1-methanol,4-(2,6-diamino-9H-purin-9-yl)-, (1R,4S)-rel-
• Synonyms: 2-Cyclopentene-1-methanol,4-(2,6-diamino-9H-purin-9-yl)-, cis- (9CI); 2-Cyclopentene-1-methanol,4-(2,6-diamino-9H-purin-9-yl)-, cis-(?à)-; NSC 614850
• CAS NO: 118237-88-0
• Molecular Formula: C₁₁H₁₄N₆O
• Molecular Weight: 246.2685
• Mol File: 118237-88-0.mol
• Article Data: 2

Chemical Properties

• Boiling Point: 628.2°Cat760mmHg
• Flash Point: 333.7°C
• Density: 1.75g/cm³
• CAS DataBase Reference: 2-Cyclopentene-1-methanol,4-(2,6-diamino-9H-purin-9-yl)-, (1R,4S)-rel-(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Cyclopentene-1-methanol,4-(2,6-diamino-9H-purin-9-yl)-, (1R,4S)-rel-(118237-88-0)
• EPA Substance Registry System: 2-Cyclopentene-1-methanol,4-(2,6-diamino-9H-purin-9-yl)-, (1R,4S)-rel-(118237-88-0)

Safety Data

• Hazardous Substances Data: 118237-88-0(Hazardous Substances Data)

Upstream product

• 118237-87-9 cis-(+/-)-2-Amino-6-chloro-9-<4-(hydroxymethyl)-2-cyclopenten-1-yl>-9H-purine 
• 76909-89-2 cis-(+/-)-3-acetoxy-5-(acetoxymethyl)cyclopentene 
• 1904-98-9 2,6-diaminopurine 
• 7686-77-3 3-cyclopentene-1-carboxylic acid 
• 130505-94-1 (1RS,4SR,6RS)-6-bromo-2-oxabicyclo<2.2.1>heptan-3-one 
• 151477-94-0 (1α,3β,4α)-(+/-)-3-bromo-4-hydroxycyclopentanemethanol 
• 122624-75-3 (+/-)-cis-<4-<<2-amino-6-chloro-5-<(4-chlorophenyl)azo>-4-pyrimidinyl>amino>-2-cyclopentenyl>carbinol 
• 122624-77-5 (+/-)-cis-<4-<(2,5-diamino-6-chloro-4-pyrimidinyl)amino>-2-cyclopentenyl>carbinol 
• 122624-73-1 (+/-)-cis-<4-<(2-amino-6-chloro-4-pyrimidinyl)amino>-2-cyclopentenyl>carbinol 
• 61865-50-7 Acetic acid 4-acetylamino-cyclopent-2-enylmethyl ester 
• 229177-39-3 1-amino-4-(hydroxymethyl)-2-cyclopentene 

Relevant articles and documents

Concise Racemic and Highly Enantioselective Approaches to Key Intermediates for the Syntheses of Carbocyclic Nucleosides and pseudo-Ribofuranoses: Formal Syntheses of Carbovir

A regio- and stereo-specific synthesis of cis-(+/-)-3-acetoxy-5-(acetoxymethyl)cyclopentene 3 from cyclopent-3-enecarboxylic acid 4 via a bromolactonisation strategy is described.Pd-catalysed coupling of the cis-(+/-)-diacetate 3 with 2-amino-6-chloropurine or 2,6-diaminopurine leads to the formal syntheses of carbovir 1.A synthesis of the (1R)-cis-diacetate 15 (R = Ac) is described via a highly enantioselective rearrangement of cis-6-oxabicyclohexane-3-methanol 13 (also prepared from the acid 4) using the dilithium salt of (1S,2R)-norephedrine.