1185453-81-9

Basic information

• Product Name: 1-(1-(4-methoxyphenyl)pyrrolidin-2-yl)propan-2-one
• Synonyms: 1-(1-(4-methoxyphenyl)pyrrolidin-2-yl)propan-2-one
• CAS NO: 1185453-81-9
• Molecular Weight: 233.31
• Mol File: 1185453-81-9.mol
• Article Data: 5

Chemical Properties

• CAS DataBase Reference: 1-(1-(4-methoxyphenyl)pyrrolidin-2-yl)propan-2-one(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(1-(4-methoxyphenyl)pyrrolidin-2-yl)propan-2-one(1185453-81-9)
• EPA Substance Registry System: 1-(1-(4-methoxyphenyl)pyrrolidin-2-yl)propan-2-one(1185453-81-9)

Safety Data

• Hazardous Substances Data: 1185453-81-9(Hazardous Substances Data)

Upstream product

• 1833-53-0 2-(Trimethylsilyloxy)propene 
• 54660-04-7 N-(4-methoxyphenyl)pyrrolidine 
• 38694-47-2 4-bromobutyraldehyde 
• 104-94-9 4-methoxy-aniline 
• 67-64-1 acetone 

Downstream Products

• 185099-67-6 N-Boc-nortropinone 

Relevant articles and documents

Tropane alkaloid compounds and method of manufacturing using sequential oxidation reactions

The present invention relates to a tropane alkaloid compound sequentially using an oxidative Mannich ring reaction and a method for producing the same. The present invention provides a tropane alkaloid compound having a structure of chemical formula 1 in

Construction of 8-Azabicyclo[3.2.1]octanes via Sequential DDQ-Mediated Oxidative Mannich Reactions of N-Aryl Pyrrolidines

A concise synthesis of 8-azabicyclo[3.2.1]octanes via sequential oxidative Mannich reactions is described. This approach involves an intermolecular oxidative Mannich coupling reaction between N-aryl pyrrolidines with TMS enol ether and a subsequent intramolecular oxidative Mannich cyclization of the corresponding silyl enol ether. DDQ is used as a key oxidant for both reactions.

Thieme Chemistry Journal Awardees - Where are they now? Aerobic oxidative coupling of tertiary amines with silyl enolates and ketene acetals

Cyclic tertiary amines can be oxidatively coupled with a variety of silyl enol ethers or ketene acetals to furnish tertiary Mannich bases. The reactions are catalyzed by simple copper salts employing elemental oxygen as the oxidant. Georg Thieme Verlag St