118665-00-2

Usage

Uses

Used in Chemical Synthesis Industry:
1,5-Dichloro-3-methyl-2-nitrobenzene is used as a chemical intermediate for the production of dyes, pigments, and pharmaceuticals. Its unique structure allows it to be a key component in the synthesis of a variety of complex organic compounds, contributing to the color and therapeutic properties of the final products.
Used in Pharmaceutical Industry:
In the pharmaceutical sector, 1,5-Dichloro-3-methyl-2-nitrobenzene serves as a precursor in the synthesis of certain drugs. Its chemical properties make it a valuable building block for the development of new medicinal compounds, potentially leading to advancements in treatment options for various health conditions.
Used in Dye and Pigment Industry:
1,5-Dichloro-3-methyl-2-nitrobenzene is utilized as a starting material in the creation of dyes and pigments. Its ability to form stable compounds with color properties is essential for the production of a wide range of colorants used in various industries, such as textiles, plastics, and printing inks.
Environmental Considerations:
Given the compound's potential toxicity and environmental impact, it is crucial that 1,5-Dichloro-3-methyl-2-nitrobenzene is handled and disposed of with care. Strict adherence to safety protocols and environmental regulations is necessary to minimize its harmful effects on aquatic life and to prevent long-term ecological damage.

Upstream product

• 25186-47-4 3,5-dichlorotoluene 

Downstream Products

• 30273-00-8 2-methyl-4,6-dichloroaniline 
• 861560-33-0 3,5-dichloro-2,4-dinitro-toluene 
• 23082-45-3 3,5-dichloro-2-nitrobenzoic acid 
• 2789-92-6 3,5-dichloroantranilic acid 
• 109553-93-7 5-methyl-2,4-dinitro-N,N'-diphenyl-m-phenylenediamine 
• 101861-15-8 5-methyl-2,4-dinitro-m-phenylenediamine 
• 131885-56-8 5-(2,4-Dimethyl-imidazol-1-yl)-3-methyl-2-nitro-phenylamine 
• 131885-55-7 3-Methyl-5-(4-methyl-imidazol-1-yl)-2-nitro-phenylamine 
• 131885-45-5 5-imidazol-1-yl-3-methyl-2-nitroaniline 
• 131886-03-8 5-(2,4-Dimethyl-imidazol-1-yl)-3-methyl-benzene-1,2-diamine 
• 131886-02-7 3-Methyl-5-(4-methyl-imidazol-1-yl)-benzene-1,2-diamine 
• 131885-95-5 2-amino-5-imidazol-1-yl-3-methylaniline 

Relevant academic research and scientific papers

Preparation method of dichlorotoluene nitride intermediate

The invention belongs to the technical field of preparation of pesticide intermediates, and particularly discloses a preparation method of a dichlorotoluene nitride intermediate. The preparation method comprises the following steps: fully reacting raw materials, a solvent and a nitration reagent to obtain a dichlorotoluene nitride intermediate, wherein the raw materials comprise any one of o-dichlorotoluene, m-dichlorotoluene and p-dichlorotoluene; the solvent is dichloroethane; the nitration reagent is concentrated nitric acid; the dichlorotoluene nitride intermediate is shown as a chemical formula 7 and a chemical formula 12. The preparation method has the advantages that the corrosion to reaction equipment is less, and the generation and discharge of waste acid and waste salt in the production process are greatly reduced.

Cardiotonic Agents. Synthesis and Cardiovascular Properties of Novel 2-Arylbenzimidazoles and Azabenzimidazoles

Novel 2-arylbenzimidazoles and azabenzimidazoles were synthesized, and their inotropic action was evaluated.Changes in left ventricular pressure, dP/dt max, were measured as an index of cardiac contractility.The structural features that impart optimal inotropic activity are presented.The most potent compounds were evaluated orally in conscious dogs with implanted Konigsberg pressure transducers.To investigate the mechanism of action, the most potent compounds were tested for their calcium-sensitizing properties and their potential for the inhibition of phosphodiesterase.Two compounds, 1 and 41, showed interesting in vitro and oral activity without side effects.They have a more potent calcium-sensitizing effect than MCI-154 and are under further investigation.