1187568-16-6

Basic information

• Product Name: 7-methoxy-3-methyl-2-phenyl-4(3H)-Quinazolinone
• Synonyms: 7-methoxy-3-methyl-2-phenyl-4(3H)-Quinazolinone;7-methoxy-3-methyl-2-phenylquinazolin-4(3H)-one;7-methoxy-3-methyl-2-phenylquinazolin-4-one
• CAS NO: 1187568-16-6
• Molecular Formula: C₁₆H₁₄N₂O₂
• Molecular Weight: 266
• Mol File: 1187568-16-6.mol
• Article Data: 6

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 7-methoxy-3-methyl-2-phenyl-4(3H)-Quinazolinone(CAS DataBase Reference)
• NIST Chemistry Reference: 7-methoxy-3-methyl-2-phenyl-4(3H)-Quinazolinone(1187568-16-6)
• EPA Substance Registry System: 7-methoxy-3-methyl-2-phenyl-4(3H)-Quinazolinone(1187568-16-6)

Safety Data

• Hazardous Substances Data: 1187568-16-6(Hazardous Substances Data)

Upstream product

• 98996-16-8 2-hydroxy-4-methoxy-N-methylbenzamide 
• 100-47-0 benzonitrile 
• 104775-67-9 2-amino-4-methoxy-N-methylbenzamide 
• 108-88-3 toluene 
• 119072-55-8 tert-butylisonitrile 
• 98-80-6 phenylboronic acid 
• 100-52-7 benzaldehyde 
• 4294-95-5 4-methoxyanthranilic acid 
• 98-88-4 benzoyl chloride 
• 593-51-1 methylamine hydrochloride 
• 35673-26-8 7-methoxy-2-phenyl-4H-benzo[d][1,3]oxazin-4-one 

Downstream Products

• 1187568-25-7 7-hydroxy-3-methyl-2-phenylquinazolin-4(3H)-one 

Relevant articles and documents

KOtBu-BF3.OEt2 mediated synthesis of quinazolin-4(3H)-ones from 2-substituted amides with nitriles and aldehydes

KOtBu-BF3.OEt2 mediated synthesis of quinazolin-4(3H)-ones from 2-substituted amides with nitriles and aldehydes have been developed. In this protocol, a variety of nitriles as well as aldehydes react with 2-substituted benzamides to corresponding quinazolin-4(3H)-ones products in good to moderate yields, via the cleavage of C-X and C-N bonds and the formation of double C-N bonds simultaneously, in presence of potassium tert-butoxide.

Palladium-Catalyzed Oxidative Three-Component Coupling of Anthranilamides with Isocyanides and Arylboronic Acids: Access to 2,3-Disubstituted Quinazolinones

A novel palladium-catalyzed oxidative three-component coupling of easily accessible N-substituted anthranilamides with isocyanides and arylboronic acids is achieved. This protocol offers an alternative approach toward 2,3-disubstituted quinazolinones with a wide substrate scope and good functional group tolerance.

COMPOUNDS AS THE ESTROGEN RELATED RECEPTORS MODULATORS AND THE USES THEREOF

The compounds according to formula VIII, their pharmaceutically acceptable acid or base addition salts, and the uses thereof is disclosed. These compounds and their pharmaceutically acceptable acid or base addition salts can be used for the preparing a me