1188355-33-0

Basic information

• Product Name: 5-Chloro-3-(3-chloropropyl)-3-(2-fluorophenyl)-6-methoxy-1-{[4-(1-methyl-ethoxy)phenyl]sulfonyl}-1,3-dihydro-2H-indol-2-one
• Synonyms: 5-Chloro-3-(3-chloropropyl)-3-(2-fluorophenyl)-6-methoxy-1-{[4-(1-methyl-ethoxy)phenyl]sulfonyl}-1,3-dihydro-2H-indol-2-one
• CAS NO: 1188355-33-0
• Molecular Weight: 566.478
• Mol File: 1188355-33-0.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 5-Chloro-3-(3-chloropropyl)-3-(2-fluorophenyl)-6-methoxy-1-{[4-(1-methyl-ethoxy)phenyl]sulfonyl}-1,3-dihydro-2H-indol-2-one(CAS DataBase Reference)
• NIST Chemistry Reference: 5-Chloro-3-(3-chloropropyl)-3-(2-fluorophenyl)-6-methoxy-1-{[4-(1-methyl-ethoxy)phenyl]sulfonyl}-1,3-dihydro-2H-indol-2-one(1188355-33-0)
• EPA Substance Registry System: 5-Chloro-3-(3-chloropropyl)-3-(2-fluorophenyl)-6-methoxy-1-{[4-(1-methyl-ethoxy)phenyl]sulfonyl}-1,3-dihydro-2H-indol-2-one(1188355-33-0)

Safety Data

• Hazardous Substances Data: 1188355-33-0(Hazardous Substances Data)

Upstream product

• 1182402-76-1 methyl (5-chloro-4-methoxy-2-nitrophenyl)(2-fluorophenyl)acetate 
• 1182402-75-0 5-Chloro-3-(2-fluorophenyl)-6-methoxy-1,3-dihydro-2H-indol-2-one 
• 98995-40-5 4-isopropoxybenzene-1-sulfonyl chloride 
• 84478-76-2 1-chloro-5-fluoro-2-methoxy-4-nitrobenzene 
• 57486-67-6 methyl o-fluorophenylacetate 

Relevant articles and documents

NOVEL 3-AMINOALKYL-1,3-DIHYDRO-2H-INDOL-2-ONE DERIVATIVES, PREPARATION THEREOF AND THERAPEUTIC USE THEREOF

The present invention relates to novel 3-aminoalkyl-1,3-dihydro-2H-indol-2-one derivatives, to their preparation and to their therapeutic application. The compounds of the present invention correspond to the formula (I): in which the variables are as set forth in the specification. These compounds exhibit a strong affinity and a high selectivity for human arginine-vasopressin (AVP) V1a receptors and some compounds additionally exhibit a strong affinity for AVP V1b receptors.