118892-73-2

Basic information

• Product Name: 2,3-Pyridinedicarboxylic acid, 2-(1-Methylethyl) ester
• Synonyms: 2,3-Pyridinedicarboxylic acid, 2-(1-Methylethyl) ester;2-(ISOPROPOXYCARBONYL)NICOTINIC ACID(WXG02574);2-(isopropoxycarbonyl)nicotinic acid;Pyridine-2,3-dicarboxylic acid 2-isopropyl ester
• CAS NO: 118892-73-2
• Molecular Formula: C₁₀H₁₁NO₄
• Molecular Weight: 209.19864
• Mol File: 118892-73-2.mol
• Article Data: 9

Chemical Properties

• Boiling Point: 384.4±27.0 °C(Predicted)
• Appearance: /
• Density: 1.256±0.06 g/cm3(Predicted)
• PKA: 2.76±0.36(Predicted)
• CAS DataBase Reference: 2,3-Pyridinedicarboxylic acid, 2-(1-Methylethyl) ester(CAS DataBase Reference)
• NIST Chemistry Reference: 2,3-Pyridinedicarboxylic acid, 2-(1-Methylethyl) ester(118892-73-2)
• EPA Substance Registry System: 2,3-Pyridinedicarboxylic acid, 2-(1-Methylethyl) ester(118892-73-2)

Safety Data

• Hazardous Substances Data: 118892-73-2(Hazardous Substances Data)

Usage

General Description

2,3-Pyridinedicarboxylic acid, 2-(1-methylethyl) ester is a chemical compound that is commonly used in the production of pharmaceuticals, agrochemicals, and other industrial applications. It is a colorless liquid with a fruity odor and is soluble in water. 2,3-Pyridinedicarboxylic acid, 2-(1-methylethyl) ester is used as a reagent in organic synthesis and as a precursor for the production of various drugs and other organic compounds. It is also used as a flavoring agent in the food industry and as an intermediate in the production of various chemicals. Additionally, it is important to handle this compound with care, as exposure to it can cause irritation to the skin, eyes, and respiratory system.

Upstream product

• 699-98-9 Pyridine-2,3-dicarboxylic anhydride 
• 67-63-0 isopropyl alcohol 
• 89-00-9 Pyridine-2,3-dicarboxylic acid 

Downstream Products

• 31181-79-0 (3-fluoropyridin-2-yl)methanol 
• 1422434-85-2 C₁₅H₁₆BrN₃O₂ 
• 1223081-81-9 5-bromo-8-(((1r,4r)-4-((tert-butoxycarbonyl)amino)cyclohexyl)amino)-1,6-naphthyridine-7-carboxylic acid 
• 1223081-79-5 tert-butyl(1r,4r)-4-(7-(methoxycarbonyl)-5-bromo-1,6-naphthyridin-8-amino)cyclohexyl carbamate 
• 410545-60-7 methyl 5-bromo-8-p-toluenesulfonyloxy-1,6-naphthyridine-7-carboxylate 
• 410544-37-5 5-bromo-8-hydroxy-[1,6]naphthyridine-7-carboxylic acid methyl ester 
• 1223081-47-7 5-bromo-7-((4-methoxybenzyl)carbamoyl)-1,6-naphthyridin-8-yl 4-methylbenzenesulfonate 
• 1223081-44-4 5-bromo-8-hydroxy-N-(4-methoxybenzyl)-1,6-naphthyridine-7-carboxamide 
• 1223081-43-3 7-(benzylcarbamoyl)-5-bromo-1,6-naphthyridin-8-yl 4-methylbenzenesulfonate 
• 1223081-42-2 N-benzyl-5-bromo-8-hydroxy-1,6-naphthyridine-7-carboxamide 
• 410542-68-6 8-hydroxy-1,6-naphthyridine-7-carboxylic acid methyl ester 

Relevant articles and documents

Novel synthesis method of 3-fluoropyridine-2-methanol

The invention relates to the field of compound preparation, in particular to a novel synthesis method of 3-fluoropyridine-2-methanol. The 3-fluoropyridine-2-methanol has a structure as shown in a formula V. According to the synthesis method, cheap quinolinic acid is used as an initial raw material, the target product namely 3-fluoropyridine-2-methanol is obtained through the steps of anhydride, esterification, ammoniation, amino fluorination, ester group reduction, and the like, and the structure of the target product is characterized by 1HNMR and 13CNMR. The synthetic method is a brand new synthetic method of 3-fluoropyridine-2-methanol, and has the advantages of low cost, simple technology, high yield, good quality, and high industrialization value.

Three substituted naphthyridine compounds and its preparation and use

The invention relates to 1,3,5-tri-substituted-1H-imidazo[4,5-h]1,6-diazanaphthalene-2(3H)-one compounds shown as the general formula I, isomers thereof and pharmaceutically acceptable salts thereof, a preparation method and applications thereof, and comp

Repositioning HIV-1 integrase inhibitors for cancer therapeutics: 1,6-naphthyridine-7-carboxamide as a promising scaffold with drug-like properties

Among a large number of HIV-1 integrase (IN) inhibitors, the 8-hydroxy-[1,6]naphthyridines (i.e., L-870,810) were one of the promising class of antiretroviral drugs developed by Merck Laboratories. In spite of its remarkable potency and efficacy, unfortun