1223081-42-2

Basic information

• Product Name: N-benzyl-5-bromo-8-hydroxy-1,6-naphthyridine-7-carboxamide
• Synonyms: N-benzyl-5-bromo-8-hydroxy-1,6-naphthyridine-7-carboxamide
• CAS NO: 1223081-42-2
• Molecular Weight: 358.194
• Mol File: 1223081-42-2.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: N-benzyl-5-bromo-8-hydroxy-1,6-naphthyridine-7-carboxamide(CAS DataBase Reference)
• NIST Chemistry Reference: N-benzyl-5-bromo-8-hydroxy-1,6-naphthyridine-7-carboxamide(1223081-42-2)
• EPA Substance Registry System: N-benzyl-5-bromo-8-hydroxy-1,6-naphthyridine-7-carboxamide(1223081-42-2)

Safety Data

• Hazardous Substances Data: 1223081-42-2(Hazardous Substances Data)

Upstream product

• 410542-68-6 8-hydroxy-1,6-naphthyridine-7-carboxylic acid methyl ester 
• 412334-35-1 3-{[methoxycarbonylmethyl-(toluene-4-sulfonyl)-amino]-methyl}-pyridine-2-carboxylic acid isopropyl ester 
• 142777-96-6 isopropyl 3-(chlorocarbonyl)pyridine-2-carboxylate 
• 118892-73-2 2,3-pyridinedicarboxylic acid 2-(isopropyl ester) 
• 699-98-9 Pyridine-2,3-dicarboxylic anhydride 
• 410544-37-5 5-bromo-8-hydroxy-[1,6]naphthyridine-7-carboxylic acid methyl ester 
• 100-46-9 benzylamine 

Downstream Products

• 1223081-43-3 7-(benzylcarbamoyl)-5-bromo-1,6-naphthyridin-8-yl 4-methylbenzenesulfonate 

Relevant articles and documents

Repositioning HIV-1 integrase inhibitors for cancer therapeutics: 1,6-naphthyridine-7-carboxamide as a promising scaffold with drug-like properties

Among a large number of HIV-1 integrase (IN) inhibitors, the 8-hydroxy-[1,6]naphthyridines (i.e., L-870,810) were one of the promising class of antiretroviral drugs developed by Merck Laboratories. In spite of its remarkable potency and efficacy, unfortun