1189116-34-4Relevant academic research and scientific papers
Fluorous bispidine: A bifunctional reagent for copper-catalyzed oxidation and knoevenagel condensation reactions in water
Ang, Wei Jie,Chng, Yong Sheng,Lam, Yulin
, p. 81415 - 81428 (2015/10/06)
Fluorous bispidine-type ligands have been developed to facilitate its recovery and reusability and to demonstrate its bifunctional property as a ligand and base in copper-catalyzed aerobic oxidation, the Knoevenagel condensation and tandem oxidation/Knoevenagel condensation in water under mild conditions. Application of the fluorous ligand was also extended to the surfactant-free copper-catalyzed allylic and benzylic sp3 C-H oxidation reaction in water. The fluorous ligands could be recovered using F-SPE with recovery ranging from 91-97% and could be reused five times with little loss of activity.
IBX-mediated dehydrogenation of substituted β-oxonitriles
Klahn, Philipp,Kirsch, Stefan F.
, p. 3149 - 3155 (2014/06/09)
A convenient method for the mild dehydrogenation of β-oxonitriles is presented. When treated with o-iodoxybenzoic acid (IBX), a range of these compounds were transformed into their unsaturated counterparts. Furthermore, we show that the products of the dehydrogenation can react in situ, undergoing rapid hetero-Diels-Alder reactions with enol ethers to give multiply substituted dihydropyrans. We also describe the dehydrogenation of cyclic β-oxonitriles, which leads to the formation of substituted phenols. Copyright
Diels-Alder reactions of acyclic α-cyano α,β-alkenones: a new approach to highly substituted cyclohexene system
Amancha, Prashanth K.,Lai, Yi-Chun,Chen, I.-Chia,Liu, Hsing-Jang,Zhu, Jia-Liang
experimental part, p. 871 - 877 (2010/03/25)
The Diels-Alder reactions of a variety of acyclic α-cyano α,β-unsaturated ketones 8 have been investigated. With the assistance of boron trichloride, these compounds were found to undergo the cycloaddition readily with dienes to give the corresponding add
Phosphine-catalyzed reaction of cyanohydrins with activated alkynes
Siby, Acetou,Loreau, Olivier,Taran, Frederic
experimental part, p. 2365 - 2370 (2010/02/28)
A new method for preparing α-cyanoacrylates and α-cyanoenones is described. The procedure uses a phosphine-catalyzed α-C addition of cyanide ion, generated in situ from cyanohydrins, to activated alkynes. An unexpected tandem reaction producing benzyliden
