118971-03-2 Usage
Uses
(S)-2-(Methoxydiphenylmethyl)pyrrolidine is a diphenylprolinol methyl ether, which can be used as a catalyst to synthesize: Enantioselective ketones via intermolecular asymmetric Michael addition of aldehydes to nonactivated enones. Stereoselective chiral bipyrazolidin-3-one derivatives by dipolar cycloaddition reaction of azomethine imines with α, β-unsaturated aldehydes. Enantioenriched spiro nitrogen heterocycles via asymmetric nucleophilic epoxidation of α-ylideneoxindole esters. Optically active secondary alcohols by asymmetric addition of Et2Zn to various aldehydes.
Check Digit Verification of cas no
The CAS Registry Mumber 118971-03-2 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,1,8,9,7 and 1 respectively; the second part has 2 digits, 0 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 118971-03:
(8*1)+(7*1)+(6*8)+(5*9)+(4*7)+(3*1)+(2*0)+(1*3)=142
142 % 10 = 2
So 118971-03-2 is a valid CAS Registry Number.
InChI:InChI=1/C18H21NO/c1-20-18(17-13-8-14-19-17,15-9-4-2-5-10-15)16-11-6-3-7-12-16/h2-7,9-12,17,19H,8,13-14H2,1H3/t17-/m0/s1
118971-03-2Relevant articles and documents
Fluorinated chiral secondary amines as catalysts for epoxidation of olefins with oxone
Ho, Chun-Yu,Chen, Ying-Chun,Wong, Man-Kin,Yang, Dan
, p. 898 - 906 (2007/10/03)
(Chemical Equation Presented) We have synthesized a series of chiral cyclic secondary amines having different substitution patterns and have screened them as catalysts for the asymmetric epoxidation of olefins using Oxone. The highest enantiomeric excess (61%) occurred for the epoxidation of 1-phenylcyclohexene catalyzed by a secondary amine bearing a fluorine atom at the β-position relative to the amino center. Our experimental results provide further support to the notion that the amine plays a dual role - as a phase transfer catalyst and an Oxone activator - in these epoxidation reactions. The slightly acidic reaction conditions we employed in this work obviate the need to preform ammonium salts, which are the actual catalysts that mediate the epoxidations.
