119030-81-8

Basic information

• Product Name: rac-(2S)-(8β,8'α)-4-benzoyloxy-3,5-dimethoxy-4',5'-methylenedioxy-2,2'-cyclolignan-9,9'-olide
• CAS NO: 119030-81-8
• Molecular Weight: 488.494
• Mol File: 119030-81-8.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: rac-(2S)-(8β,8'α)-4-benzoyloxy-3,5-dimethoxy-4',5'-methylenedioxy-2,2'-cyclolignan-9,9'-olide(CAS DataBase Reference)
• NIST Chemistry Reference: rac-(2S)-(8β,8'α)-4-benzoyloxy-3,5-dimethoxy-4',5'-methylenedioxy-2,2'-cyclolignan-9,9'-olide(119030-81-8)
• EPA Substance Registry System: rac-(2S)-(8β,8'α)-4-benzoyloxy-3,5-dimethoxy-4',5'-methylenedioxy-2,2'-cyclolignan-9,9'-olide(119030-81-8)

Safety Data

• Hazardous Substances Data: 119030-81-8(Hazardous Substances Data)

Upstream product

• 134-96-3 syringic aldehyde 
• 119030-77-2 4-benzyloxy-3,5-dimethoxybenzyl alcohol 
• 119030-76-1 4-benzyloxy-3,5-dimethoxybenzaldehyde 
• 98-88-4 benzoyl chloride 
• 69146-92-5 4-benzoyloxy-3,5-dimethoxybenzyl bromide 
• 80483-34-7 4-(1,3-benzodioxol-5-ylmethyl)-4,5-dihydrofuran-2(3H)-one 
• 119030-79-4 rac-(8α,8'β)-4'-benzoyloxy-3',5'-dimethoxy-3,4-methylenedioxylignan-9',9-olide 

Relevant articles and documents

Oxidative Coupling of Lignans. IV. Monophenolic Oxidative Coupling

Oxidative coupling of the monophenolic monoester (6) gives an aryltetralin (12) which is a potential intermediate for the synthesis of clinically active monophenolic lignan lactones.In contrast, oxidative couplings of the monophenols (32) and (35), derived from matairesinol (29), give mixtures of diastereoisomeric cyclooctadiene lignans while 4'-demethyldeoxypodorhizon (26) does not cyclize.These results show that the degree of aromatic substitution in monophenolic diarylbutanes plays an important role in determining the outcome of oxidative coupling.An alternative synthesis of the lactone (57) from piperonal has been investigated.