1190364-33-0Relevant academic research and scientific papers
Real-time monitoring of a cobalt-mediated one-pot transition metal-catalyzed multicomponent reaction
Crotti, Ant?nio E. M.,Donate, Paulo M.,Previdi, Daniel,Scott McIndoe, J.
, (2020)
In this paper, pressurized sample infusion electrospray ionization mass spectrometry (PSI-ESI-MS) and FTIR spectroscopy were used to investigate the mechanism of a like-Barbier cobalt-mediated one-pot transition metal-catalyzed multicomponent reaction (MC
Synthesis and cytotoxic evaluation of novel paraconic acid analogs
Le Floch, Camille,Le Gall, Erwan,Léonel, Eric,Martens, Thierry,Cresteil, Thierry
experimental part, p. 7054 - 7058 (2012/01/06)
A novel class of 2,3-tri- and tetrasubstituted γ-butyrolactones analogous to paraconic acids has been synthesized in one step using a straightforward three-component reaction among aryl bromides, dimethyl itaconate and carbonyl compounds. The in vitro cyt
A cobalt-catalyzed multicomponent approach to novel 2,3-Di-and 2,2,3-trisubstituted 3-methoxycarbonyl-γ-butyrolactones
Le Floch, Camille,Le Gall, Erwan,Leonel, Eric,Koubaa, Jihen,Martens, Thierry,Retailleau, Pascal
experimental part, p. 5279 - 5286 (2010/11/17)
A one-pot, three-component synthesis of the title butyrolactones starting from aryl bromides, dimethyl itaconate, and either aldehydes or ketones is described. The cobalt-catalyzed domino process formally involves the in situ metalation of an aromatic bromide, conjugate addition onto dimethyl itaconate, an aldolization reaction with a carbonyl compound and a final cyclization into a five-membered lactone. This procedure is applied to the concise synthesis of a range of functionalized γ-butyrolactones with a methyl paraconate subunit.
Three-component synthesis of functionalized five-membered ring lactones under Barbier-like conditions
Floch, Camille Le,Bughin, Carine,Gall, Erwan Le,Léonel, Eric,Martens, Thierry
experimental part, p. 5456 - 5458 (2010/01/11)
Five-membered ring lactones have been synthesized using a straightforward three-component reaction among in situ-generated arylzinc reagents, dimethyl itaconate and aromatic aldehydes. This Barbier-like procedure, which is characterized by its simplicity,
