1190991-74-2Relevant articles and documents
A Pd(ii)/Mg-La mixed oxide catalyst for cyanation of aryl C-H bonds and tandem Suzuki-cyanation reactions
Kishore, Ramineni,Yadav, Jagjit,Venu, Boosa,Venugopal, Akula,Lakshmi Kantam
, p. 5259 - 5264 (2015)
A palladium(ii)/magnesium-lanthanum mixed oxide (Pd(ii)/Mg-La) catalyst is a reusable catalyst for cyanation of aromatic C-H bonds by using the combination of NH4HCO3 and DMSO as the ''CN'' source. Moderate to good yields of aromatic nitriles were obtained. An excellent regioselectivity was achieved using the present protocol. A tandem process involving Suzuki coupling followed by a cyanation reaction was also developed using the heterogeneous (Pd(ii)/Mg-La) catalyst. This cascade process resulted in the formation of aromatic nitrile from simple 2-halopyridine. The catalyst was recovered by centrifugation and reused for three consecutive cycles with nearly consistent activity and selectivity. This journal is
Rhodium-Catalyzed Direct C-H Bond Cyanation in Ionic Liquids
Lv, Songyang,Li, Yaling,Yao, Tian,Yu, Xinling,Zhang, Chen,Hai, Li,Wu, Yong
supporting information, p. 4994 - 4997 (2018/08/24)
A Cp?Rh(III)/IL-based direct C-H bond cyanation system was developed for the first time. The system is a mild, efficient, and recyclable method for the synthesis of aryl nitriles. Many different directing groups can be used in this cyanation, and the reaction tolerates a variety of functional groups.
Copper-mediated C-H cyanation of (hetero)arenes with ethyl (ethoxymethylene)cyanoacetate as a cyanating agent
Qi, Chaorong,Hu, Xiaohan,Jiang, Huanfeng
supporting information, p. 7994 - 7997 (2017/07/22)
A copper-mediated direct C-H cyanation of (hetero)arenes with ethyl (ethoxymethylene)cyanoacetate as a safe cyanating agent has been successfully developed by using molecular oxygen as the oxidant. The reaction tolerates a variety of functional groups and provides a facile and efficient method for the synthesis of a wide range of (hetero)aryl nitriles.
