1191391-89-5Relevant academic research and scientific papers
Anodic oxidation on a boron-doped diamond electrode mediated by methoxy radicals
Sumi, Takenori,Saitoh, Tsuyoshi,Natsui, Keisuke,Yamamoto, Takashi,Atobe, Mahito,Einaga, Yasuaki,Nishiyama, Shigeru
supporting information; experimental part, p. 5443 - 5446 (2012/07/14)
Direct evidence: The existence of methoxy radical species formed during an anodic oxidation in MeOH on a boron-doped diamond (BDD) electrode was confirmed by ESR spectroscopy. Effective production of a neolignan, licarinA, was accomplished by the BDD-medi
Efficient synthesis of (±)-parasitenone, a novel inhibitor of NF-κB
Saitoh, Tsuyoshi,Suzuki, Eriko,Takasugi, Arisa,Obata, Rika,Ishikawa, Yuichi,Umezawa, Kazuo,Nishiyama, Shigeru
scheme or table, p. 5383 - 5386 (2010/08/06)
Dehydroxymethylepoxyquinomicin (DHMEQ, 1) is a novel nuclear factor-κB (NF-κB) inhibitor that inhibits DNA binding of NF-κB components including p65. To inspect its biological activity of 1, we synthesized parasitenone (3), possessing the common epoxycyclohexenone moiety of 1. Assessment of the inhibitory activity against NF-κB indicated that the epoxycyclohexenone moiety is the most essential element for the NF-κB inhibitory activity and the salicylic acid moiety may contribute the binding efficiency and specificity.
