1192309-52-6

Basic information

• Product Name: 1-{4-Chloro-3-[2-(2-dimethylamino-ethylamino)-8-methoxy-7-oxo-7,8-dihydropyrido[2,3-d]pyrimidin-6-yl]-phenyl}-3-(3-chloro-4-methoxy-phenyl)-urea
• Synonyms: 1-{4-Chloro-3-[2-(2-dimethylamino-ethylamino)-8-methoxy-7-oxo-7,8-dihydropyrido[2,3-d]pyrimidin-6-yl]-phenyl}-3-(3-chloro-4-methoxy-phenyl)-urea
• CAS NO: 1192309-52-6
• Molecular Weight: 572.451
• Mol File: 1192309-52-6.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 1-{4-Chloro-3-[2-(2-dimethylamino-ethylamino)-8-methoxy-7-oxo-7,8-dihydropyrido[2,3-d]pyrimidin-6-yl]-phenyl}-3-(3-chloro-4-methoxy-phenyl)-urea(CAS DataBase Reference)
• NIST Chemistry Reference: 1-{4-Chloro-3-[2-(2-dimethylamino-ethylamino)-8-methoxy-7-oxo-7,8-dihydropyrido[2,3-d]pyrimidin-6-yl]-phenyl}-3-(3-chloro-4-methoxy-phenyl)-urea(1192309-52-6)
• EPA Substance Registry System: 1-{4-Chloro-3-[2-(2-dimethylamino-ethylamino)-8-methoxy-7-oxo-7,8-dihydropyrido[2,3-d]pyrimidin-6-yl]-phenyl}-3-(3-chloro-4-methoxy-phenyl)-urea(1192309-52-6)

Safety Data

• Hazardous Substances Data: 1192309-52-6(Hazardous Substances Data)

Upstream product

• 1192310-23-8 6-(2-chloro-5-nitrophenyl)-2-(2-(dimethylamino)ethylamino)-8-methoxypyrido[2,3-d]pyrimidin-7(8H)-one 
• 1192310-22-7 6-(2-chloro-5-nitrophenyl)-8-methoxy-2-(methylsulfonyl)pyrido[2,3-d]pyrimidin-7(8H)-one 
• 1192310-21-6 6-(2-chloro-5-nitrophenyl)-8-methoxy-2-(methylthio)pyrido[2,3-d]pyrimidin-7(8H)-one 
• 1192310-19-2 2-(2-chloro-5-nitrophenyl)-N-methoxyacetamide 
• 1044145-59-6 [4-chloro-2-(methylsulfanyl)pyrimidin-5-yl]methanol 
• 148256-82-0 4-chloro-2-(methylsulfanyl)pyrimidine-5-carboxaldehyde 
• 37777-70-1 2-(2-chloro-5-nitrophenyl)acetic acid 
• 5909-24-0 4-chloro-2-methanesulfanylpyrimidine-5-carboxylic acid ethyl ester 
• 2444-36-2 2'-chloro-benzeneacetic acid 
• 1192310-18-1 6-(5-amino-2-chlorophenyl)-2-(2-(dimethylamino)ethylamino)-8-methoxypyrido[2,3-d]pyrimidin-7(8H)-one 
• 28395-76-8 3-chloro-4-methoxyphenylisocyanate 

Relevant articles and documents

RAF INHIBITORS

The present invention provides derivatives of pyrido[2,3-d]pyrimidin-7-one. These compounds are inhibitors or kinases such as Raf, including compounds that show anti-proliferative activity, including against tumor cells, and are useful in the treatment of