1193244-89-1

Basic information

• Product Name: 2-(5-bromopyrimidin-2-yl)propan-2-ol
• Synonyms: 2-(5-bromopyrimidin-2-yl)propan-2-ol;2-(5-BROMOPYRIMIDIN-2-YL)PROPAN-2-OL 9-BOC-3,9-DIAZA-BICYCLO[3.3.1]NONANE;EOS-60710;2-(5-BROMOPYRIMIDIN-2-YL)PROPAN-2-OL\n9-BOC-3,9-DIAZA-BICYCLO[3.3.1]NONANE(WXC05145)
• CAS NO: 1193244-89-1
• Molecular Formula: C7H9BrN2O
• Molecular Weight: 217.06316
• Mol File: 1193244-89-1.mol
• Article Data: 3

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 2-(5-bromopyrimidin-2-yl)propan-2-ol(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(5-bromopyrimidin-2-yl)propan-2-ol(1193244-89-1)
• EPA Substance Registry System: 2-(5-bromopyrimidin-2-yl)propan-2-ol(1193244-89-1)

Safety Data

• Hazardous Substances Data: 1193244-89-1(Hazardous Substances Data)

Usage

Uses

2-(5-Bromopyrimidin-2-yl)propan-2-ol is a reactant in the preparation of aminobenzimidazole urea as an antibacterial agent.

Upstream product

• 89581-38-4 5-bromopyrimidine-2-carboxylic acid methyl ester 
• 75-16-1 methylmagnesium bromide 
• 1197193-30-8 ethyl 5-bromopyrimidine-2-carboxylate 
• 67-64-1 acetone 
• 183438-24-6 5-bromo-2-iodopyrimidine 

Downstream Products

• 1319255-87-2 2-(5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyrimidin-2-yl)propan-2-ol 
• 1459772-35-0 2-(5-bromopyrimidin-2-yl)propan-2-yl 4-nitrophenyl carbonate 
• 1615683-42-5 2-(5-(4-amino-3-(3-fluoropyridin-2-yl)-5-nitrophenyl)-pyrimidin-2-yl)propan-2-ol 

Relevant articles and documents

FUSED TRICYCLIC IMIDAZOLE DERIVATIVES AS MODULATORS OF TNF ACTIVITY

A series of fused tricyclic imidazole derivatives, in particular dihydro-1H-cyclopenta[4,5]imidazo[1,2-a]pyridine derivatives, and analogues thereof, being potent modulators of human TNFα activity, are accordingly of benefit in the treatment and/or prevention of various human ailments, including autoimmune and inflammatory disorders; neurological and neurodegenerative disorders; pain and nociceptive disorders; cardiovascular disorders; metabolic disorders; ocular disorders; and oncological disorders.

Antibacterial Compounds

The present invention provides a compound of the following formula, salts, racemates, diastereomers, enantiomers, esters, carbamates, phosphates, sulfates, deuterated forms and prodrugs thereof. Also provided is the use of these compounds as antibacterials, compositions comprising them and processes for their manufacture.