1194-97-4

Basic information

• Product Name: Methyl 5-Methyl-1H-pyrrole-2-carboxylate
• Synonyms: Methyl 5-Methyl-1H-pyrrole-2-carboxylate;1H-Pyrrole-2-carboxylicacid, 5-methyl-, methyl ester
• CAS NO: 1194-97-4
• Molecular Formula: C₇H₉NO₂
• Molecular Weight: 139.15186
• Mol File: 1194-97-4.mol
• Article Data: 9

Chemical Properties

• Melting Point: 93-94 °C
• Boiling Point: 250.2°Cat760mmHg
• Flash Point: 105.1°C
• Appearance: /
• Density: 1.141g/cm³
• Vapor Pressure: 0.022mmHg at 25°C
• Refractive Index: 1.523
• Storage Temp.: under inert gas (nitrogen or Argon) at 2-8°C
• PKA: 15.89±0.50(Predicted)
• CAS DataBase Reference: Methyl 5-Methyl-1H-pyrrole-2-carboxylate(CAS DataBase Reference)
• NIST Chemistry Reference: Methyl 5-Methyl-1H-pyrrole-2-carboxylate(1194-97-4)
• EPA Substance Registry System: Methyl 5-Methyl-1H-pyrrole-2-carboxylate(1194-97-4)

Safety Data

• Hazardous Substances Data: 1194-97-4(Hazardous Substances Data)

Usage

Uses

5-Methyl-2-(methoxycarbonyl)pyrrole is one of the chemical compounds detected from smoke condensate of 70mm nonfiltered cigarettes.

InChI:InChI=1/C7H9NO2/c1-5-3-4-6(8-5)7(9)10-2/h3-4,8H,1-2H3

Upstream product

• 186581-53-3 diazomethane 
• 3757-53-7 5-methyl-1H-pyrrole-2-carboxylic acid 
• 67-56-1 methanol 
• 183268-72-6 2,2,2-trichloro-1-(5-methyl-1H-pyrrol-2-yl)ethan-1-one 
• 124-41-4 sodium methylate 
• 1000682-45-0 (2Z,4E)-methyl 2-azidohexa-2,4-dienoate 
• 3284-51-3 ethyl 5-methyl-1H-pyrrole-2-carboxylate 
• 636-41-9 2-methyl-1H-pyrrole 
• 116635-17-7 1-<(2,6-dimethyl-4-oxo-4H-<1>benzopyrano<3,4-d>oxazol-7-yl)oxy>-2-acetoxy-4-methoxy-5,5-dimethyl-3-tetrahydropyranyl 5-methyl-1H-pyrrole-2-carboxylate 

Downstream Products

• 203208-33-7 4-(2-Chloro-acetyl)-5-methyl-1H-pyrrole-2-carboxylic acid methyl ester 
• 203207-18-5 4-Bromo-2-carbomethoxy-5-methylpyrrol 

Relevant articles and documents

PYRROLE mTORC INHIBITORS AND USES THEREOF

The present invention provides compounds, compositions thereof, and methods of using the same.

Inexpensive Radical Methylation and Related Alkylations of Heteroarenes

A simple method for the introduction of a methyl and higher aliphatic group to various heteroarenes using very inexpensive reagents is described. It is based on the radical addition of a carboxylic xanthate followed by decarboxylation. Depending on the heteroarene structure, the decarboxylation can be spontaneous or induced by heating in N,N-dimethylacetamide or N-methyl pyrrolidone in a microwave oven.

Visible-light sensitization of vinyl azides by transition-metal photocatalysis

Irradiation of vinyl and aryl azides with visible light in the presence of Ru photocatalysts results in the formation of reactive nitrenes, which can undergo a variety of C-N bond-forming reactions. The ability to use low-energy visible light instead of UV in the photochemical activation of azides avoids competitive photodecomposition processes that have long been a significant limitation on the synthetic use of these reactions. Rock and pyrrole: Irradiation of vinyl and aryl azides with visible light in the presence of Ru photocatalysts results in the formation of reactive nitrenes, which can undergo a variety of C-N bond-forming reactions. The ability to use low-energy visible light instead of UV in the photochemical activation of azides (see picture) avoids competitive photodecomposition processes. Copyright