119458-82-1

Upstream product

• 123-11-5 4-methoxy-benzaldehyde 
• 89-25-8 edaravone 
• 39143-07-2 4-anisylidene-3-methyl-1-phenylpyrazol-5-one 
• 942-32-5 5-methyl-2-phenyl-2H-pyrazol-3-ol 
• 141-97-9 ethyl acetoacetate 
• 100-63-0 phenylhydrazine 
• 3585-93-1 N-(4-methoxybenzylidene)aniline oxide 

Relevant academic research and scientific papers

Melamine trisulfunic acid: An efficient and recyclable solid acid catalyst for the synthesis of 4,4′-(arylmethylene)-bis-(1H-pyrazol-5-ols)

Melamine trisulfunic acid is employed as a recyclable catalyst for the condensation reaction of aromatic aldehydes with 3-methyl-l-phenyl-2-pyrazolin- 5-one. This condensation reaction was performed in ethanol under refluxing conditions giving 4,4′-(arylm

Design and Characterization of l-Prolinate-Amberlite as a Novel Heterogeneous Organocatalyst and Its Catalytic Application in the Synthesis of Pyrazol-Derivates

The [Amb]l-prolinate obtained from the immobilization of l-prolinate anion onto amberlite IRA900OH, was used as a new organocatalyst for the efficient synthesis of 4,4′-(arylmethylene)-bis-(1H-pyrazol-5-ol) derivatives. The prepared heterogeneous organoca

One-pot efficient pseudo-five-components synthesis of 4,4′-(arylmethylene)bis(3-methyl-1-phenyl-1H-pyrazol-5-ols) at room temperature assisted by K2CO3

A convenient approach for the synthesis of 4,4′-(arylmethylene)-bis(3-methyl-1-phenyl-1H-pyrazol-5-ols) by an efficient one-pot reaction of aromatic aldehydes, phenylhydrazine, and ethyl acetoacetate by using substoichiometric amount of K2COsu

Novel drug-based Fe(III) heterochelates: Synthetic, spectroscopic, thermal and in-vitro antibacterial significance

A series of novel heterochelates of the type [Fe(An)(L)(H 2O)2]*MH2O[where H2A n = 4,4'-(arylmethylene)bis(3-methyl-1-phenyl-4,5-dihydro-1H-pyrazol- 5-ol); aryl = 4-nitrophenyl, m = 1(Hsub

Synthesis of nano magnetite Fe3O4 based vanadic acid: A highly efficient and recyclable novel nanocatalyst for the synthesis of 4,4′-(arylmethylene)-bis(3-methyl-1-phenyl-1H-pyrazol-5-ols)

Nano magnetic Fe3O4 based vanadic acid [MNPs@VO(OH)2] (average diameter 20-26 nm) has been synthesized by grafting VOCl3 on the Fe3O4 surface nanoparticles as a retrievable supporter to pro

Green and efficient synthesis of novel bispyrazoles through a tandem Knoevenagel and Michael type reaction using nanowire zinc oxide as a powerful and recyclable catalyst

Zinc oxide nanowires (ZnO NWs) were prepared and characterized by scanning electron microscopy, powder X-ray diffraction, and transmission electron microscopy analyses. ZnO NWs were then employed as heterogeneous and recyclable catalyst for green synthesi

Sulfonated nanohydroxyapatite functionalized with 2-aminoethyl dihydrogen phosphate (HAP@AEPH2-SO3H) as a new recyclable and eco-friendly catalyst for rapid one-pot synthesis of 4,4′-(aryl methylene)bis(3-methyl-1H-pyrazol-5-ol)s

Sulfonated nanohydroxyapatite functionalized with 2-aminoethyl dihydrogen phosphate (HAP@AEPH2-SO3H), a new green, recyclable solid acid catalyst, was prepared and characterized using FT-IR, XRD, SEM, TEM and TGA/DTA techniques. The

Efficient pseudo five-component synthesis of 4,4′-(arylmethylene)-bis(3-methyl-1-phenyl-1H-pyrazol-5-ol) derivatives promoted by a novel ionic liquid catalyst

In this research, initial production and characterization of a novel Br?nsted-acidic ionic liquid, namely, N,N,N′,N′-tetramethylethylenediaminium-N,N′-disulfonic acid hydrogen sulfate ([TMEDSA][HSO4]2), has been described (characteri

Ni-guanidine@MCM-41 NPs: a new catalyst for the synthesis of 4,4?-(arylmethylene)-bis-(3-methyl-1-phenyl-1H-pyrazol-5-ols) and symmetric di-aryl sulfides

In this work, the surface of mesoporous MCM-41 was modified with guanidine, and then, Nickel particles have become immobilized on its surface (Ni-guanidine@MCM-41NPs). This heterogeneous catalyst has been identified by various techniques including: low-angle X-ray diffraction, scanning electron microscopy, energy-dispersive X-ray spectroscopy, inductively coupled plasma, thermal gravimetric analysis and N2 adsorption–desorption measurement isotherms, and its catalytic application was studied in the synthesis of 4,4?-(arylmethylene)-bis-(3-methyl-1-phenyl-1H-pyrazol-5-ol) derivatives and symmetric di-aryl sulfides. The prepared organometallic complex could be isolated, post-reaction, by simple filtration for several consecutive cycles without a notable change in its catalytic activity.

The Solid-State Michael Addition of 3-Methyl-1-phenyl-5-pyrazolone

A novel solid-state Michael addition between pyrazolone 1 and 4-arylidenepyrazolones 2 at ambient temperature produced Michael adducts, 4,4′-arylidenebis(3-methyl-1-phenyl-5-pyrazolones) 3. Pyrazolones 3 formed salts 4 with Cu2+ in solution, indicating the enolic structure of the pyrazolone rings. The reactivity of 2 with 1 is discussed in terms of the electronic and steric effects of the substituent on the arylidene group of compounds 2. Pyrazolone 1 also underwent the solid state Michael addition reaction with maleimide at 100° to give the adducts 7, 8 and 9.