1195-06-8Relevant academic research and scientific papers
Catalytic hydrogenation of 2,4-dinitroethylbenzene to 2,4- diaminoethylbenzene over Ni/HY catalysts: The solvent effect
Ren, Bin,Zhao, Minghui,Dong, Lichun,Li, Guixian
, p. 92 - 96 (2014)
Catalytic hydrogenation of 2,4-dinitroethylbenzene over Ni/HY catalysts in different solvents was studied, which demonstrated that the reaction exhibits the best performance in protic solvents. The reason is hypothesized to be the strong hydrogen-bond interaction between the protic solvents with the reactant, intermediates and product due to their excellent hydrogen-bond donating capability, which favors the desorption of the adsorbed intermediates and product from the catalysts and helps to polarize the NO bonds of the reactant and intermediates. Subsequently, the hydrogenation in the mixed solvents of water and ethanol was investigated, which showed that the reaction can be significantly accelerated by adding water into ethanol and the optimum volume percentage of water is verified to be 40%.
MODULATORS OF ATP-BINDING CASSETTE TRANSPORTERS
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, (2012/12/14)
The present invention relates to modulators of ATP-Binding Cassette (“ABC”) transporters or fragments thereof, including Cystic Fibrosis Transmembrane Conductance Regulator, compositions thereof, and methods therewith. The present invention also relates to methods of treating ABC transporter mediated diseases using such modulators.
COMPOSITIONS FOR TREATMENT OF CYSTIC FIBROSIS AND OTHER CHRONIC DISEASES
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, (2012/04/23)
The present invention relates to pharmaceutical compositions comprising an inhibitor of epithelial sodium channel activity in combination with at least one ABC Transporter modulator compound of Formula A, Formula B, Formula C, or Formula D. The invention also relates to pharmaceutical formulations thereof, and to methods of using such compositions in the treatment of CFTR mediated diseases, particularly cystic fibrosis using the pharmaceutical combination compositions.
Triazinyl reactive dyestuffs in which triazinyl group is further substituted with a beta-chloroethylsulfonyl- or vinylsulfonylbutyrylamino moiety
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, (2008/06/13)
Reactive dyes of the formula STR1 in which D is the radical of an organic dye of the monoazo, polyazo, metal complex azo, anthraquinone, phthalocyanine, formazan, azomethine, dioxazine, phenazine, stilbene, triphenylmethane, xanthene, thioxanthrone, nitroaryl, naphthoquinone, pyrenequinone or perylenetetracarbimide series, R is hydrogen or substituted or unsubstituted C1-4 -alkyl, X is a substituent which is detachable as an anion, B is a radical of the formula STR2 R1 and R2, independently of each other, are hydrogen or substituted or unsubstituted C1-4 -alkyl or phenyl, A is a substituted or unsubstituted aliphatic or aromatic bridge member, Y is a --CO--Z or --SO2 --Z radical, Z is an aliphatic, aromatic or heterocyclic reactive radical, and n is 1 or 2, are suitable for dyeing or printing cellulose-containing and nitrogen-containing materials and in high dyeing yield produce dyeings and prints having good fastness properties.
