1204-29-1

Basic information

• Product Name: 1-ethyl-2,4-dinitrobenzene
• Synonyms: 1-Ethyl-2,4-dinitrobenzene
• CAS NO: 1204-29-1
• Molecular Formula: C₈H₈N₂O₄
• Molecular Weight: 196.1601
• EINECS: 214-875-3
• Mol File: 1204-29-1.mol
• Article Data: 8

Chemical Properties

• Boiling Point: 304.6°C at 760 mmHg
• Flash Point: 143.4°C
• Density: 1.344g/cm³
• Vapor Pressure: 0.00156mmHg at 25°C
• Refractive Index: 1.584
• CAS DataBase Reference: 1-ethyl-2,4-dinitrobenzene(CAS DataBase Reference)
• NIST Chemistry Reference: 1-ethyl-2,4-dinitrobenzene(1204-29-1)
• EPA Substance Registry System: 1-ethyl-2,4-dinitrobenzene(1204-29-1)

Safety Data

• Hazardous Substances Data: 1204-29-1(Hazardous Substances Data)

Usage

General Description

1-ethyl-2,4-dinitrobenzene is a chemical compound that belongs to the nitrobenzene family and is commonly used as a raw material in the production of dyes and pesticides. It is a pale yellow crystalline solid with a nitro group attached to the 2 and 4 positions of the benzene ring, and an ethyl group attached to the 1 position. The chemical is known for its strong odor and is considered toxic and harmful if inhaled or ingested. It is also a known skin and eye irritant, and exposure to high levels of 1-ethyl-2,4-dinitrobenzene can cause symptoms such as headaches, nausea, and dizziness. Additionally, it is a flammable substance and should be handled with care.

Upstream product

• 100-41-4 ethylbenzene 
• 97-00-7 1-chloro-2,4-dinitro-benzene 

Downstream Products

• 20191-74-6 2-ethyl-5-nitroaniline 
• 5805-89-0 N-(4-ethyl-3-nitrophenyl)acetamide 
• 611-03-0 4-amino-2-aminobenzoic acid 
• 51529-96-5 4-ethyl-3-nitroaniline 
• 610-30-0 2,4-dinitrobenzoic acid 
• 62572-86-5 1-(2,4-dinitrophenyl)ethanone 
• 1195-06-8 1,3-diamino-4-ethyl-benzene 
• 13985-60-9 2-ethyl-1,3,5-trinitrobenzene 
• 94632-41-4 ethyl phloroglucinol 

Relevant articles and documents

NITRATION OF AROMATIC COMPOUNDS

The present invention provides a process for nitrating aromatic compounds without the need for a solid catalyst and/or any organic solvents and/or any other additives. A typical process includes combining or admixing a nitric acid and an anhydride compound under conditions sufficient to produce a reactive intermediate. The aromatic compound to be nitrated is then added to this reactive intermediate to produce a nitroaromatic compound. The nitroaromatic compound can be substituted with one or more, typically, one to three, and often one or two nitrate (-NO2) groups.

Highly regioselective dinitration of toluene over reusable zeolite Hβ

A nitration system comprising nitric acid, propanoic anhydride, and zeolite Hβ has been developed for dinitration of toluene to give 2,4-dinitrotoluene in 98% yield, with a 2,4-:2,6-dinitrotoluene ratio of over 120. This represents the most selective quantitative method for 2,4-dinitration of toluene; the catalyst is reusable, solvent is not needed, and an aqueous work-up is not required.

PHOSPHODIESTERASE 10 INHIBITORS

The present invention if directed to certain cinnoline compounds that are PDE10 inhibitors, pharmaceutical compositions containing such compounds and processes for preparing such compounds. The invention is also directed to methods of treating diseases mediated by PDE10 enzyme, such as obesity, non-insulin dependent diabetes, schizophrenia, bipolar disorder, obsessive-compulsive disorder, and the like.