119550-16-2Relevant academic research and scientific papers
Bond-Switch Rearrangement of 3-Oxo-Δ4-1,2,4-thiadiazolin-5-yl Ureas
L'abbe, Gerrit,Albrecht, Ernestine,Toppet, Suzanne
, p. 1619 - 1624 (2007/10/02)
5-Amino-3-oxo-Δ4-1,2,4-thiadiazolines 5a,b react with isocyanates to yield 1,2,4-thiadiazolidine derivatives 9a-d via bond switching of the corresponding isomers 7.The same type of products 9e-m was obtained by treatment of 5-amino-1,2,3,4-thia
Covalent Adduct Formation in 1,2,4-Thiadiazolo Activated Pyrimidinones
Keilen, Gunnar,Undheim, Kjell
, p. 362 - 366 (2007/10/02)
Preparation of 1-(1,2,4-thiadiazol-5-yl)-2(1H)-pyrimidinones is described.The polarization from the thiadiazole ring enhances the ?-electron deficiency of the pyrimidine ring.The latter forms covalently bound adducts with hydroxylic solvent molecules in a regiospecific manner.The adducts are stable, isolable molecules, but on heating in a hydroxylic solvent exchange of the solvent molecule in the adduct may take place.
