78972-46-0

Upstream product

• 103-85-5 monophenylthiourea 
• 137577-21-0 C₂₂H₂₁N₃OS 
• 28269-82-1 1-phenyl-2-S-benzyl isothiocarbamide 
• 78972-53-9 6-Anilino-2,3-dihydro-2-thioxo-4H-1,3,5-thiadiazin-4-on 
• 100-46-9 benzylamine 

Downstream Products

• 137577-11-8 5-Benzylcarbamoylimino-2-(p-nitrophenyl)-4-phenyl-1,2,4-thiadiazolidin-3-one 
• 137577-10-7 5-Benzylcarbamoylimino-2-isopropyl-4-phenyl-1,2,4-thiadiazolidin-3-one 
• 119550-16-2 5-Anilino-2-benzyl-3-oxo-Δ⁴-1,2,4-thiadiazoline 

Relevant academic research and scientific papers

Bond-Switch Rearrangement of 3-Oxo-Δ4-1,2,4-thiadiazolin-5-yl Ureas

5-Amino-3-oxo-Δ4-1,2,4-thiadiazolines 5a,b react with isocyanates to yield 1,2,4-thiadiazolidine derivatives 9a-d via bond switching of the corresponding isomers 7.The same type of products 9e-m was obtained by treatment of 5-amino-1,2,3,4-thia

Carbonyl Diisothiocyanate

A cheap synthesis of carbonyl diisothiocyanate (1) from ammonium thiocyanate and phosgene is reported.As a strong electrophil 1 forms the 6-substituted 2-thioxo-1,3,5-thiadiazine-4-ones 4 - 7 with water, alcohols, hydrogensulfide, mercaptanes, ammonia, and amines.With excess nucleophil the ring of the heterocycles is opened.Addition to the NCS group or substitution of this group leads to compounds 9, 11, 12, 14, and 15.Thermally the thiadiazinones 7e, h rearrange to the dithioisocyanuric acids 10a, b.Some physical properties ( e. g. pK values, hindered rotations) of the compounds are described.