1196547-77-9

Upstream product

• 6775-78-6 6-chloroimidazo[1,2-b]pyridazine 
• 13526-66-4 3-bromo-6-chloro-imidazo[1,2-b]pyridazine 
• 1196551-99-1 tert-butyl 2-(2,5-difluorophenyl)-2-hydroxypyrrole-1-carboxylate 
• 1443623-92-4 5-(2,5-difluorophenyl)-3,4-dihydro-2H-pyrrole 
• 886503-15-7 rac-2-(2,5-difluorophenyl)pyrrolidine 
• 399-94-0 2-bromo-1,4-difluorobenzene 
• 1025744-38-0 2-fluoro-6-tributylstannanyl-pyridine 
• 1196551-98-0 3-bromo-6-(2-(2,5-difluorophenyl)pyrrolidin-1-yl)imidazo[1,2-b]pyridazine 

Downstream Products

• 1196547-96-2 1-(6-(6-(2-(2,5-difluorophenyl)pyrrolidin-1-yl)imidazo[1,2-b]pyridazin-3-yl)pyridin-2-yl)piperidin-4-ol 

Relevant academic research and scientific papers

COMPOUNDS AND COMPOSITIONS AS KINASE INHIBITORS

The invention provides compounds, pharmaceutical compositions comprising such compounds and methods of using such compounds to treat or prevent diseases or disorders associated with abnormal or deregulated kinase activity, particularly Ros, KDR, FMS, c-FMS, FLT3, c-Kit, JAK2, JAK3, Aurora, PDGFR, Lck, TrkA, TrkB, TrkC, IGF-1R, ALK4, ALK5 and ALK or combinations thereof.