119701-95-0

Basic information

• Product Name: Phosphinic amide, N-[(4-methoxyphenyl)methylene]-P,P-diphenyl-
• CAS NO: 119701-95-0
• Molecular Formula: C20H18NO2P
• Molecular Weight: 335.342
• Mol File: 119701-95-0.mol
• Article Data: 15

Chemical Properties

• CAS DataBase Reference: Phosphinic amide, N-[(4-methoxyphenyl)methylene]-P,P-diphenyl-(CAS DataBase Reference)
• NIST Chemistry Reference: Phosphinic amide, N-[(4-methoxyphenyl)methylene]-P,P-diphenyl-(119701-95-0)
• EPA Substance Registry System: Phosphinic amide, N-[(4-methoxyphenyl)methylene]-P,P-diphenyl-(119701-95-0)

Safety Data

• Hazardous Substances Data: 119701-95-0(Hazardous Substances Data)

Upstream product

• 123-11-5 4-methoxy-benzaldehyde 
• 3717-21-3 p-methoxyl benzaldoxime 
• 1079-66-9 chloro-diphenylphosphine 
• 2403-58-9 4-methoxybenzaldehyde diethylacetal 
• 5994-87-6 diphenylphosphinamide 
• 1499-21-4 Diphenylphosphinic chloride 
• 1707-03-5 diphenyl-phosphinic acid 

Downstream Products

• 1215194-82-3 N-(2-(9H-fluoren-9-ylideneamino)-1-(4-methoxyphenyl)ethyl)-P,P-diphenylphosphinic amide 
• 1402577-49-4 (3'R,5S)-1-(diphenylphosphoryl)-5-(4-methoxyphenyl)-1'-methyl-2-thioxospiro[imidazolidine-4,3'-indolin]-2'-one 
• 892494-01-8 N-[1-(4-methoxyphenyl)propyl]-P,P-diphenylphosphinic amide 

Relevant articles and documents

Enantioselective Mannich Reaction of Glycine Iminoesters with N-Phosphinoyl Imines: A Bifunctional Approach

A bifunctional catalytic approach for the asymmetric Mannich reaction of glycine iminoesters with N-phosphinoyl imines has been developed. By the combination of metal catalysis and organocatalysis, the vicinal two stereogenic centers were efficiently constructed, affording a wide range of syn-diamino esters in high yields with excellent enantio- and diastereoselectivities (up to >99:1 dr, 99% ee).

Iron-Catalyzed Asymmetric Nitro-Mannich Reaction

The first enantioselective addition of nitroalkanes to imines (nitro-Mannich reaction), mediated by an iron(II) catalyst assembled by a hindered hydroxyethyl-pybox ligand, is described. This valuable carbon-carbon bond-forming reaction proceeds smoothly at room temperature to afford enantioenriched β-nitro amines in good yields and high enantioselectivity, up to 98% with unprecedentedly low iron catalyst loading (5 mol %).

(Thiolan-2-yl)diphenylmethyl benzyl ether/N,N′-diarylurea cocatalyzed asymmetric aziridination of cinnamyl bromide and aryl aldimine

A dual catalyst system using THT-based chiral sulfide 2a and H-bond donor 10a was developed for the asymmetric imino Corey-Chaykovsky reaction. Under the optimum reaction conditions, cinnamyl bromide reacted with a wide scope of N-diphenylphosphinic aldim