1197849-57-2

Basic information

• Product Name: ethyl 2-(2-(4-chlorophenyl)imidazo[1,2-a]pyridin-3-yl)acetate
• Synonyms: ethyl 2-(2-(4-chlorophenyl)imidazo[1,2-a]pyridin-3-yl)acetate
• CAS NO: 1197849-57-2
• Molecular Weight: 314.771
• Mol File: 1197849-57-2.mol
• Article Data: 7

Chemical Properties

• CAS DataBase Reference: ethyl 2-(2-(4-chlorophenyl)imidazo[1,2-a]pyridin-3-yl)acetate(CAS DataBase Reference)
• NIST Chemistry Reference: ethyl 2-(2-(4-chlorophenyl)imidazo[1,2-a]pyridin-3-yl)acetate(1197849-57-2)
• EPA Substance Registry System: ethyl 2-(2-(4-chlorophenyl)imidazo[1,2-a]pyridin-3-yl)acetate(1197849-57-2)

Safety Data

• Hazardous Substances Data: 1197849-57-2(Hazardous Substances Data)

Upstream product

• 623-73-4 diazoacetic acid ethyl ester 
• 38922-74-6 2-(4-chlorophenyl)imidazolo[1,2-a]pyridine 
• 504-29-0 2-aminopyridine 
• 104-88-1 4-chlorobenzaldehyde 
• 623-47-2 propynoic acid ethyl ester 
• 3278-34-0 ethyl 2-(ethoxythiocarbonylthio)acetate 
• 59045-98-6 N-(4-chlorobenzylidene)pyridin-2-amine 
• 53503-49-4 ethyl 4-(4-chlorophenyl)-4-oxobutanoate 
• 706-07-0 1-chloro-4-(2-nitrovinyl)benzene 
• 1381932-40-6 C₁₄H₁₄ClNO₆ 

Downstream Products

• 1197849-28-7 2-(4-chlorophenyl)-3-((5-(pyridin-2-yl)-4H-1,2,4-triazol-3-yl)methyl)imidazo[1,2-a]pyridine 
• 1197849-35-6 5-((2-(4-chlorophenyl)imidazo[1,2-a]pyridin-3-yl)methyl)-N-methyl-1,3,4-thiadiazol-2-amine 
• 1197849-60-7 2-(2-(4-chlorophenyl)imidazo[1,2-a]pyridin-3-yl)acetohydrazide 

Relevant articles and documents

Magnetic nanostructure-anchored mixed-donor ligand system based on carboxamide and N-heterocyclic thiones: An efficient support of CuI catalyst for synthesis of imidazo[1,2-a]pyridines in eutectic medium

A Cu-incorporated nanocatalyst has been developed by immobilizing copper iodide on a magnetically retrievable mixed-donor ligand system, containing carboxamide, imidazolidine-2-thione and imidazole-2-thione donor groups and characterized by various analys

Magnetic Cu0@HAP@γ-Fe2O3 nanoparticles: An efficient catalyst for one-pot three-component reaction for the synthesis of imidazo[1,2-a]pyridines

Cu(0) incorporated magnetic hydroxyapatite nanoparticles (Cu0@HAP@γ-Fe2O3 NPs) was conveniently synthesized via the ion exchange reaction, oxidation, and reduction steps. The structure and composition of the nanohybrid wer

Copper(II)-Mediated Aerobic Synthesis of Imidazo[1,2-a]pyridines via Cascade Aminomethylation/Cycloisomerization of Alkynes

A single copper(II)-catalyzed three-component cascade aminomethylation/cycloisomerization of propiolates to form imidazo[1,2-a]pyridines was explored. A straightforward method was developed for the practical synthesis of functionalized imidazo[1,2-a]pyridines from benzaldehydes, 2-aminopyridines, and propiolate derivatives catalyzed by Cu(OAc)2 hydrate in the presence of air. The protocol is marked by excellent yields, functional group tolerance, and, above all, adaptability to synthesize imidazo[1,2-a]pyridine-based drug molecules such as Alpidem.