1198-56-7

Usage

Appearance

Colorless to light yellow solid Describes the physical appearance of the compound as either colorless or with a light yellow hue in its solid state.

Primary use

Intermediate in chemical production -主要用于作为生产各种化学品（如药品、杀虫剂和染料)的中间体。

Classification

Halogenated aromatic hydrocarbon A type of organic compound containing carbon and hydrogen atoms, with additional halogen atoms (such as chlorine and fluorine) bonded to the aromatic ring.

Environmental impact

Environmental pollutant Due to its toxic effects on aquatic organisms and potential for bioaccumulation in the food chain, it is considered an environmental pollutant.

Health effects

Respiratory and skin irritant Exposure to 1,2,3,5-Tetrachloro-4,6-difluorobenzene can cause irritation in the respiratory system and on the skin.

Human health risks

Adverse health effects Associated with various negative health effects in humans, which can result from direct contact or environmental exposure.

Regulation

Strictly regulated production and use The compound's production and use are regulated to minimize potential risks to the environment and human health.

Upstream product

• 1435-43-4 1-chloro-3,5-difluorobenzene 
• 827-06-5 2,4,5,6-Tetrabromo-1,3-difluorobenzene 
• 827-10-1 1,3-Difluor-4,6-dichlor-2,5-dibrombenzol 
• 118-74-1 hexachlorobenzene 
• 392-56-3 Hexafluorobenzene 
• 348-57-2 2,4-difluorobromobenzene 
• 372-18-9 1,3-Difluorobenzene 
• 2253-30-7 1,3-dichloro-4,6-difluorobenzene 
• 108-70-3 1,3,5-trichlorobenzene 

Downstream Products

• 26288-19-7 2,4,5,6-Tetrachlor-1,3-phenylendiamin 
• 62477-10-5 2,4,5,6-Tetrachlor-1,3-phenylendiamintetraacetat 
• 319-88-0 1,3,5-trichlorotrifluorobenzene 

Relevant academic research and scientific papers

METHOD FOR THE PRODUCTION OF 1,3,5-TRIFLUORO-2,4,6-TRICHLOROBENZENE FROM FLUOROBENZENE DERIVATIVES

Method for the production of 1,3,5-trifluoro-2,4,6-trichlorobenzene from fluorobenzene, comprising steps A) and B): A) chlorination of fluorobenzene derivatives of formula (II), in which X = fluorine or H, Z = nitro, bromo or chloro and n = 0 or 1-4 and B) fluorination of the distillation residue and separation by distillation of the 1,3,5-trifluoro-2,4,6-trichlorobenzene thus produced.

Chloro- and bromo-defluorination of hexafluorobenzene and octafluorotoluene

Halo(chloro, bromo)defluorination of perfluorobenzaene and toluene efficiently occurs under the action of appropriate alkali metal halides in the presence of hexaethylguanidinium chloride in catalytic amount. The relative efficiency of halide anions and m

Catalytic fluorination of hexachlorobenzene with supported potassium fluoride

Fluorination of hexachlorobenzene with potassium fluoride supported on calcium fluoride or barium fluoride with using quaternary phosphonium salt as a phase-transfer catalyst was studied, and a synergism was observed.

AROMATIC FLUORINE CHEMISTRY. PART 4. PREPARATION OF 2,6-DIFLUOROANILINE

The preparation of 2,6-difluoroaniline from 1,3,5-trichlorobenzene is described. 1-Chloro-3,5-difluorobenzene prepared via KF exchange on 1,3,5-trichlorobenzene is dichlorinated and nitrated in a single reactor to a mixture of trichlorodifluoronitrobenzenes.The latter are reduced to ca. 4:1 mixture of 2,6-difluoroaniline and 2,4-difluoroaniline.