1199-20-8

Basic information

• Product Name: 3-Phenylbut-2-enoic acid
• Synonyms: B-METHYLCINNAMIC ACID;3-PHENYLBUT-2-ENOIC ACID;beta-Methylcinnamicacid;3-Phenyl-2-butenoic acid
• CAS NO: 1199-20-8
• Molecular Formula: C₁₀H₁₀O₂
• Molecular Weight: 162.19
• EINECS: 221-199-2
• Mol File: 1199-20-8.mol
• Article Data: 16

Chemical Properties

• Boiling Point: 281.926 °C at 760 mmHg
• Flash Point: 188.218 °C
• Appearance: /
• Density: 1.119 g/cm³
• Vapor Pressure: 0.00164mmHg at 25°C
• Refractive Index: 1.561
• CAS DataBase Reference: 3-Phenylbut-2-enoic acid(CAS DataBase Reference)
• NIST Chemistry Reference: 3-Phenylbut-2-enoic acid(1199-20-8)
• EPA Substance Registry System: 3-Phenylbut-2-enoic acid(1199-20-8)

Safety Data

• Hazardous Substances Data: 1199-20-8(Hazardous Substances Data)

Usage

Synthesis Reference(s)

Journal of the American Chemical Society, 86, p. 2645, 1964 DOI: 10.1021/ja01067a026Tetrahedron Letters, 36, p. 2469, 1995 DOI: 10.1016/0040-4039(95)00285-K

InChI:InChI=1/C10H10O2/c1-8(7-10(11)12)9-5-3-2-4-6-9/h2-7H,1H3,(H,11,12)/b8-7+

Upstream product

• 98-86-2 acetophenone 
• 124-38-9 carbon dioxide 
• 91-66-7 N,N-diethylaniline 
• 98-83-9 isopropenylbenzene 
• 209065-57-6 2-[bis(2,2,2-trifluoroethoxy)phosphoryl]acetic acid 
• 113426-20-3 C₁₄H₁₈O₂ 
• 121-69-7 N,N-dimethyl-aniline 
• 1504-72-9 ethyl 3-phenylbut-2-enoate 
• 552-82-9 benzhydrylidene(methyl)amine 

Downstream Products

• 4593-90-2 3-phenylbutyric acid 
• 80854-59-7 β-methyl-4-nitrocinnamic acid 
• 102548-30-1 2,3-dibromo-3-phenyl-butyric acid 
• 98-83-9 isopropenylbenzene 
• 71001-35-9 (2-bromoprop-1-en-1-yl)benzene 
• 68204-17-1 3-phenylbut-2-enoyl chloride 
• 3360-55-2 β-chloro-α-methylstyrene 
• 19647-26-8 (Z)-β-bromo-α-methylstyrene 
• 16917-35-4 (E)-(1-bromoprop-1-en-2-yl)benzene 
• 70453-19-9 (E)-3-phenylbut-2-enoyl chloride 
• 68204-17-1 (Z)-3-phenylbut-2-enoyl chloride 
• 51384-73-7 4-phenyl-3-penten-2-one 
• 17977-00-3 4-Methoxy-4-phenyl-pentanon-⁽²⁾ 
• 17913-16-5 rac.-α-2.4-Diphenyl-4-methoxy-pentanol-(2) 

Relevant articles and documents

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Photocarboxylation in the Presence of Aromatic Amines and Carbon Dioxide

Phenylethylenes (1), biphenyl, and 1-methyl-2-phenylindole underwent carboxylation upon photolysis in the presence of aromatic amines (2) and carbon dioxide.

Construction of Multi-Substituted Benzenes via NHC-Catalyzed Reactions of Carboxylic Esters

A carbene-catalyzed ester activation reaction for the synthesis of multi-substituted benzenes is developed. Tetra-substituted benzene compounds are efficiently synthesized through this methodology. Compared with aldehyde substrates used in previous reports, the ester substrates used here are much more readily available and inexpensive. In addition, the TEMPO oxidant used here is more inexpensive than the quinones commonly used in related carbene-catalyzed reactions.

Pd-Catalyzed α-Selective C-H Functionalization of Olefins: En Route to 4-Imino-β-Lactams

Pd-catalyzed α-olefinic C-H activation of simple α,β-unsaturated olefins has been developed. 4-imino-β-lactam derivatives were readily synthesized via activation of α-olefinic C-H bonds with excellent cis stereoselectivity. A wide range of heterocycles at the β-position are compatible with this reaction. The product of 4-imino-β-lactam derivatives can be readily converted to 2-aminoquinoline which exists extensively in pharmaceutical drugs and natural products.