119993-19-0

Upstream product

• 4070-48-8 L-Valine methyl ester 
• 123-11-5 4-methoxy-benzaldehyde 
• 45821-44-1 4-methoxy-benzylideneamine 
• 5619-05-6 DL-valine methyl ester hydrochloride 
• 6306-52-1 L-valine methylester hydrochloride 

Downstream Products

• 132599-70-3 N-<(S)-1-(methoxycarbonyl)-2-methylpropyl>-(6R)-2,3-didehydro-6-(4-methoxyphenyl)piperidin-4-one 
• 132599-71-4 N-<(S)-1-(methoxycarbonyl)-2-methylpropyl>-(6S)-2,3-didehydro-6-(4-methoxyphenyl)piperidin-4-one 
• 119993-44-1 dimethyl 2-isopropyl-c-5-p-methoxyphenyl-r-2-t-4-pyrrolidinedicarboxylate 
• 119993-44-1 dimethyl 2-isopropyl-t-5-p-methoxyphenyl-r-2-c-4-pyrrolidinedicarboxylate 
• 119993-24-7 dimethyl N-p-methoxybenzylidene-2-isopropylglutamate 
• 119993-25-8 methyl N-p-methoxybenzylidene-2-(2'-cyanoethyl)valinate 
• 104739-64-2 N-(2-Boc-amino-3-phenylpropyliden)-L-valin-N-oxid-methylester 
• 872984-86-6 (S)-2-[3-(4-Methoxy-phenyl)-oxaziridin-2-yl]-3-methyl-butyric acid methyl ester 

Relevant academic research and scientific papers

A simple protocol for NMR analysis of the enantiomeric purity of chiral hydroxylamines

A practically simple three-component chiral derivatization protocol for determining the enantiopurity of chiral hydroxylamines by 1H NMR spectroscopic analysis is described, involving their treatment with 2-formylphenylboronic acid and enantiopure BINOL to afford a mixture of diastereomeric nitrono-boronate esters whose ratio is an accurate reflection of the enantiopurity of the parent hydroxylamine.

A convenient method for the enantiomeric separation of α-amino acid esters as benzophenone imine schiff base derivatives

A convenient liquid chromatographic method for the separation of α-amino acid esters as benzophenone Schiff base derivatives on coated chiral stationary phases (CSPs) (Chiralcel OD-H, Chiralcel OD, Chiralpak AD-H, Chiralpak AD, and Chiralpak AS) or covalently immobilized CSPs (Chiralpak IA, Chiralpak IB, and Chiralpak IC) derived from polysaccharide derivatives is described. Benzophenone imine derivatives of α-amino acid esters were readily prepared by stirring benzophenone imine and the hydrochloride salts of α-amino acid esters in 2-propanol. The chromatographic separations were conducted at a flow rate 1.0 mL/min and a detection wavelength of 254 nm; 0.5% 2-propanol/hexane (v/v) was used on CSPs. In general, the resolution of Chiralpak IC was superior to those of the other CSPs. In addition, the resolutions of other arylimine derivatives of α-amino acid esters and the effects of different mobile phases on the enantiomeric separation of α-amino acid esters as benzophenone imine derivatives on Chiralpak IC were investigated.

"Nitrono" Peptides, I. - An Isomeric and Isoelectronic Equivalent of the Peptide Bond

Optically active Boc-α-L-amino aldehydes 1 are converted with N-hydroxy-α-L-amino acid methyl esters 2 into the N-blocked "nitrono" dipeptide esters 3a-l.